17-AAG 1PC X 500UG

cas: 75747-14-7 — see every product listed under this CAS number, including other names

17-AAG 1PC X 500UG (CAS 75747-14-7) is a chemical reagent available from Chemat. Available pack sizes: 500UG. Offered by: Sigma-Aldrich.

brandSigma-Aldrich
catalog number100068-500UG
cas75747-14-7
size500UG
availability availability
Documents: Safety Data Sheet (MSDS)
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Available pack sizes

brand size price
Sigma-Aldrich 500UG 1360.00 Pln

properties

purityNo data
delivery time1-2 weeks (only if in stock, to check click on availability)
Structural formula: {0} (CAS {1})

Tanespimycin is a 19-membered macrocyle that is geldanamycin in which the methoxy substituent attached to the benzoquinone moiety has been replaced by an allylamino group. It is a potent inhibitor of heat shock protein 90 (Hsp90). A less toxic analogue than geldanamycin, it induces apoptosis and displays antitumour effects. It has a role as an antineoplastic agent, a Hsp90 inhibitor and an apoptosis inducer. It is a member of 1,4-benzoquinones, an ansamycin, a carbamate ester, an organic heterobicyclic compound and a secondary amino compound. It is functionally related to a geldanamycin.

Source: ChEBI

Identity
Molecular formulaC31H43N3O8
Molecular weight585.7 g/mol
IUPAC name[(4E,6Z,8S,9S,10E,12S,13R,14S,16R)-13-hydroxy-8,14-dimethoxy-4,10,12,16-tetramethyl-3,20,22-trioxo-19-(prop-2-enylamino)-2-azabicyclo[16.3.1]docosa-1(21),4,6,10,18-pentaen-9-yl] carbamate
InChIKeyAYUNIORJHRXIBJ-TXHRRWQRSA-N
SMILESC[C@H]1C[C@@H]([C@@H]([C@H](/C=C(/[C@@H]([C@H](/C=C\C=C(\C(=O)NC2=CC(=O)C(=C(C1)C2=O)NCC=C)/C)OC)OC(=O)N)\C)C)O)OC

Computed by PubChem (NCBI)

Synonyms: Tanespimycin, 17-(Allylamino)-17-demethoxygeldanamycin, 17-(Allylamino)geldanamycin, tanespimycine, tanespimicina, tanespimycinum, 17-Demethoxy-17-allylamino geldanamycin, 17-demethoxy-17-(2-propenylamino)geldanamycin, Geldanamycin, 17-demethoxy-17-(2-propenylamino)-, 17-N-allylamino-17-demethoxygeldanamycin

Also listed as

17-Allylamino-17-Demethoxygeldanamycin Chemat Brand CAS 75747-14-7
17-(Allylamino) Geldanamycin, >95% (HPLC) TRC CAS 75747-14-7
17–AAG (KOS953) GLPBio CAS 75747-14-7
Tanespimycin/ 99.83% (existing batch purity) TargetMol CAS 75747-14-7
17-(Allylamino)-17-demethoxygeldanamycin, 99% Thermo Scientific (Alfa Aesar) CAS 75747-14-7
17-Allylaminogeldanamycin Biosynth CAS 75747-14-7
Telatinib, 98.00% Chemat CAS 75747-14-7
Tanespimycin 98% Ambeed CAS 75747-14-7
17-(ALLYLAMINO)-17-DEMETHOXYGELDANAMYCIN Sigma-Aldrich CAS 75747-14-7
17-AAG, 98%, 98% Chemat CAS 75747-14-7
17-Allylaminogeldanamycin, min. 95 %, 5 mg Roth CAS 75747-14-7
17-Allylaminogeldanamycin, min. 95 %, 10 mg Roth CAS 75747-14-7
17-Allylaminogeldanamycin, min. 95 %, 25 mg Roth CAS 75747-14-7
Tanespimycin, 99.01% MedChemExpress CAS 75747-14-7
Tanespimycin (Standard), 98.72% MedChemExpress CAS 75747-14-7
17-Allylamino-17-Demethoxygeldanamycin-d5 Chemat Brand CAS 75747-14-7 (non-labelled)
17-Allylamino-17-Demethoxygeldanamycin-d5 Hubei YoungXin CAS 75747-14-7(non-labelled)