Tanespimycin 98%

cas: 75747-14-7 — see every product listed under this CAS number, including other names

Tanespimycin 98% (CAS 75747-14-7) is a chemical reagent available from Chemat. Available pack sizes: 1mg, 5mg, 10mg, 25mg, 50mg, 100mg, 250mg. Offered by: Ambeed.

brandAmbeed
catalog numberA220462-1mg
cas75747-14-7
size1mg
Documents: Safety Data Sheet (MSDS)
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Available pack sizes

brand size price
Ambeed 1mg 186.81 Pln
Ambeed 5mg 231.31 Pln
Ambeed 10mg 320.31 Pln
Ambeed 25mg 487.19 Pln
Ambeed 50mg 904.38 Pln
Ambeed 100mg 1121.31 Pln
Ambeed 250mg 2701.06 Pln

properties

purity98%
delivery time 1-2 weeks
ambeed catalog no.A220462
Structural formula: {0} (CAS {1})

Tanespimycin is a 19-membered macrocyle that is geldanamycin in which the methoxy substituent attached to the benzoquinone moiety has been replaced by an allylamino group. It is a potent inhibitor of heat shock protein 90 (Hsp90). A less toxic analogue than geldanamycin, it induces apoptosis and displays antitumour effects. It has a role as an antineoplastic agent, a Hsp90 inhibitor and an apoptosis inducer. It is a member of 1,4-benzoquinones, an ansamycin, a carbamate ester, an organic heterobicyclic compound and a secondary amino compound. It is functionally related to a geldanamycin.

Source: ChEBI

Identity
Molecular formulaC31H43N3O8
Molecular weight585.7 g/mol
IUPAC name[(4E,6Z,8S,9S,10E,12S,13R,14S,16R)-13-hydroxy-8,14-dimethoxy-4,10,12,16-tetramethyl-3,20,22-trioxo-19-(prop-2-enylamino)-2-azabicyclo[16.3.1]docosa-1(21),4,6,10,18-pentaen-9-yl] carbamate
InChIKeyAYUNIORJHRXIBJ-TXHRRWQRSA-N
SMILESC[C@H]1C[C@@H]([C@@H]([C@H](/C=C(/[C@@H]([C@H](/C=C\C=C(\C(=O)NC2=CC(=O)C(=C(C1)C2=O)NCC=C)/C)OC)OC(=O)N)\C)C)O)OC

Computed by PubChem (NCBI)

Synonyms: Tanespimycin, 17-(Allylamino)-17-demethoxygeldanamycin, 17-(Allylamino)geldanamycin, tanespimycine, tanespimicina, tanespimycinum, 17-Demethoxy-17-allylamino geldanamycin, 17-demethoxy-17-(2-propenylamino)geldanamycin, Geldanamycin, 17-demethoxy-17-(2-propenylamino)-, 17-N-allylamino-17-demethoxygeldanamycin

Also listed as

17-Allylamino-17-Demethoxygeldanamycin Chemat Brand CAS 75747-14-7
17-(Allylamino) Geldanamycin, >95% (HPLC) TRC CAS 75747-14-7
17–AAG (KOS953) GLPBio CAS 75747-14-7
Tanespimycin/ 99.83% (existing batch purity) TargetMol CAS 75747-14-7
17-(Allylamino)-17-demethoxygeldanamycin, 99% Thermo Scientific (Alfa Aesar) CAS 75747-14-7
17-Allylaminogeldanamycin Biosynth CAS 75747-14-7
Telatinib, 98.00% Chemat CAS 75747-14-7
17-(ALLYLAMINO)-17-DEMETHOXYGELDANAMYCIN Sigma-Aldrich CAS 75747-14-7
17-AAG 1PC X 500UG Sigma-Aldrich CAS 75747-14-7
17-AAG, 98%, 98% Chemat CAS 75747-14-7
17-Allylaminogeldanamycin, min. 95 %, 5 mg Roth CAS 75747-14-7
17-Allylaminogeldanamycin, min. 95 %, 10 mg Roth CAS 75747-14-7
17-Allylaminogeldanamycin, min. 95 %, 25 mg Roth CAS 75747-14-7
Tanespimycin, 99.01% MedChemExpress CAS 75747-14-7
Tanespimycin (Standard), 98.72% MedChemExpress CAS 75747-14-7
17-Allylamino-17-Demethoxygeldanamycin-d5 Chemat Brand CAS 75747-14-7 (non-labelled)
17-Allylamino-17-Demethoxygeldanamycin-d5 Hubei YoungXin CAS 75747-14-7(non-labelled)