17-AAG, 98%, 98%
cas: 75747-14-7 — see every product listed under this CAS number, including other names
17-AAG, 98%, 98% (CAS 75747-14-7) is a chemical reagent available from Chemat. Available pack sizes: 1mg, 5mg, 10mg, 25mg, 50mg, 100mg, 250mg. Offered by: Chemat.
| brand | Chemat |
|---|---|
| catalog number | Ch116IF6-1mg |
| cas | 75747-14-7 |
| size | 1mg |
| availability | 1.25g |
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Available pack sizes
| brand | size | price | |
|---|---|---|---|
| Chemat | 1mg | 165.20 Pln | |
| Chemat | 5mg | 184.40 Pln | |
| Chemat | 10mg | 304.40 Pln | |
| Chemat | 25mg | 477.20 Pln | |
| Chemat | 50mg | 683.60 Pln | |
| Chemat | 100mg | 995.60 Pln | |
| Chemat | 250mg | 2402.00 Pln |
properties
| purity | 98% |
|---|---|
| delivery time | 3 weeks |
Tanespimycin is a 19-membered macrocyle that is geldanamycin in which the methoxy substituent attached to the benzoquinone moiety has been replaced by an allylamino group. It is a potent inhibitor of heat shock protein 90 (Hsp90). A less toxic analogue than geldanamycin, it induces apoptosis and displays antitumour effects. It has a role as an antineoplastic agent, a Hsp90 inhibitor and an apoptosis inducer. It is a member of 1,4-benzoquinones, an ansamycin, a carbamate ester, an organic heterobicyclic compound and a secondary amino compound. It is functionally related to a geldanamycin.
Source: ChEBI
| Molecular formula | C31H43N3O8 |
|---|---|
| Molecular weight | 585.7 g/mol |
| IUPAC name | [(4E,6Z,8S,9S,10E,12S,13R,14S,16R)-13-hydroxy-8,14-dimethoxy-4,10,12,16-tetramethyl-3,20,22-trioxo-19-(prop-2-enylamino)-2-azabicyclo[16.3.1]docosa-1(21),4,6,10,18-pentaen-9-yl] carbamate |
| InChIKey | AYUNIORJHRXIBJ-TXHRRWQRSA-N |
| SMILES | C[C@H]1C[C@@H]([C@@H]([C@H](/C=C(/[C@@H]([C@H](/C=C\C=C(\C(=O)NC2=CC(=O)C(=C(C1)C2=O)NCC=C)/C)OC)OC(=O)N)\C)C)O)OC |
Computed by PubChem (NCBI)
Synonyms:
Tanespimycin, 17-(Allylamino)-17-demethoxygeldanamycin, 17-(Allylamino)geldanamycin, tanespimycine, tanespimicina, tanespimycinum, 17-Demethoxy-17-allylamino geldanamycin, 17-demethoxy-17-(2-propenylamino)geldanamycin, Geldanamycin, 17-demethoxy-17-(2-propenylamino)-, 17-N-allylamino-17-demethoxygeldanamycin