6–diazo–5–oxo–L–nor–Leucine

cas: 157-03-9 — see every product listed under this CAS number, including other names

6–diazo–5–oxo–L–nor–Leucine (CAS 157-03-9) is a chemical reagent available from Chemat. Available pack sizes: 10mg, 25mg, 5mg, 50mg. Offered by: GLPBio.

brandGLPBio
catalog numberGC41224-10
cas157-03-9
size10mg

Available pack sizes

brand size price
GLPBio 10mg 1004.24 Pln
GLPBio 25mg 1776.53 Pln
GLPBio 5mg 728.09 Pln
GLPBio 50mg 2853.04 Pln

properties

purityNo data
delivery timeTo be confirmed by Chemat
Structural formula: {0} (CAS {1})

6-diazo-5-oxo-L-norleucine is a non-proteinogenic L-alpha-amino acid that is L-norleucine which is substituted at position 5 by an oxo group and at position 6 by a diazo group. It is as inhibitor of various glutamine-utilising enzymes. It has a role as an EC 6.3.5.5 [carbamoyl-phosphate synthase (glutamine-hydrolysing)] inhibitor, an EC 6.3.4.2 [CTP synthase (glutamine hydrolyzing)] inhibitor, an EC 6.3.5.3 (phosphoribosylformylglycinamidine synthase) inhibitor, an EC 6.3.5.2 [GMP synthase (glutamine-hydrolysing)] inhibitor, a glutamine antagonist, an EC 2.4.2.14 (amidophosphoribosyltransferase) inhibitor, an EC 6.3.5.1 [NAD(+) synthase (glutamine-hydrolysing)] inhibitor, an EC 6.3.5.4 [asparagine synthase (glutamine-hydrolysing)] inhibitor, an antiviral agent, an antibacterial agent, an antimetabolite, an analgesic, an antineoplastic agent, an EC 3.5.1.2 (glutaminase) inhibitor, an apoptosis inducer and a bacterial metabolite. It is a ketone, a diazo compound and a non-proteinogenic L-alpha-amino acid. It is a tautomer of a 6-diazo-5-oxo-L-norleucine zwitterion.

Source: ChEBI

Identity
Molecular formulaC6H9N3O3
Molecular weight171.15 g/mol
IUPAC name(2S)-2-amino-6-diazo-5-oxohexanoic acid
InChIKeyYCWQAMGASJSUIP-YFKPBYRVSA-N
SMILESC(CC(=O)C=[N+]=[N-])[C@@H](C(=O)O)N

Computed by PubChem (NCBI)

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