AR-42, 98.52%
cas: 935881-37-1 — see every product listed under this CAS number, including other names
AR-42, 98.52% (CAS 935881-37-1) is a chemical reagent available from Chemat. Available pack sizes: 10 mg, 25 mg, 100 mg, 5 mg, 10mM/1mL, 50 mg. Offered by: MedChemExpress.
| brand | MedChemExpress |
|---|---|
| catalog number | HY-13265-10 mg |
| cas | 935881-37-1 |
| size | 10 mg |
| availability | In stock |
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Available pack sizes
| brand | size | price | |
|---|---|---|---|
| MedChemExpress | 10 mg | 886.26 Pln | |
| MedChemExpress | 25 mg | 1657.16 Pln | |
| MedChemExpress | 100 mg | 3909.50 Pln | |
| MedChemExpress | 5 mg | 575.11 Pln | |
| MedChemExpress | 10mM/1mL | 621.55 Pln | |
| MedChemExpress | 50 mg | 2613.83 Pln |
properties
| delivery time | 1-2 weeks |
|---|---|
| purity | 98.52% |
AR-42 is a secondary carboxamide resulting from the formal condensation of the carboxy group of (2S)-3-methyl-2-phenylbutanoic acid with the amino group of 4-amino-N-hydroxybenzamide. It is a pan-HDAC inhibitor that was in clinical development for the treatment of hematological malignancies and solid tumours. It has a role as an antineoplastic agent, an angiogenesis inhibitor, an EC 3.5.1.98 (histone deacetylase) inhibitor and an apoptosis inducer. It is a secondary carboxamide, a member of benzenes and a hydroxamic acid.
Source: ChEBI
| Molecular formula | C18H20N2O3 |
|---|---|
| Molecular weight | 312.4 g/mol |
| IUPAC name | N-hydroxy-4-[[(2S)-3-methyl-2-phenylbutanoyl]amino]benzamide |
| InChIKey | LAMIXXKAWNLXOC-INIZCTEOSA-N |
| SMILES | CC(C)[C@@H](C1=CC=CC=C1)C(=O)NC2=CC=C(C=C2)C(=O)NO |
Computed by PubChem (NCBI)
Synonyms:
(S)-N-Hydroxy-4-(3-methyl-2-phenylbutanamido)benzamide, N-hydroxy-4-[[(2S)-3-methyl-2-phenylbutanoyl]amino]benzamide, Rec-2282, N-hydroxy-4-[(2S)-3-methyl-2-phenylbutanamido]benzamide, N-Hydroxy-4-(3-methyl-2-(S)phenyl-butyrylamino)benzamide, (S)-(+)-N-Hydroxy-4-(3-methyl-2-phenyl-butyrylamino)-benzamide, N-hydroxy-4-((2S)-3-methyl-2-phenylbutanamido)benzamide, N-hydroxy-4-(((2S)-3-methyl-2-phenylbutanoyl)amino)benzamide, N-hydroxy-4-{[(2S)-3-methyl-2-phenylbutanoyl]amino}benzamide, orb1222983