Products 136470-78-5
CAS 136470-78-5 appears in our catalog under these names: Abacavir (1.0 mg/mL in Methanol), Abacavir, >95% (HPLC), Abacavir/ 99.81% (existing batch purity), Abacavir, Abacavir - Bio-X â„¢. Offered by: TRC, TargetMol, GLPBio, Biosynth, TCI. Available pack sizes: 5x1ml, 100mg, 10mg, 50mg, 1g, 5mg, 25mg, 200mg.
Abacavir is a 2,6-diaminopurine that is (1S)-cyclopent-2-en-1-ylmethanol in which the pro-R hydrogen at the 4-position is substituted by a 2-amino-6-(cyclopropylamino)-9H-purin-9-yl group. A nucleoside analogue reverse transcriptase inhibitor (NRTI) with antiretroviral activity against HIV, it is used (particularly as the sulfate) with other antiretrovirals in combination therapy of HIV infection. It has a role as an antiviral drug, a HIV-1 reverse transcriptase inhibitor and a drug allergen.
Source: ChEBI
| Molecular formula | C14H18N6O |
|---|---|
| Molecular weight | 286.33 g/mol |
| IUPAC name | [(1S,4R)-4-[2-amino-6-(cyclopropylamino)purin-9-yl]cyclopent-2-en-1-yl]methanol |
| InChIKey | MCGSCOLBFJQGHM-SCZZXKLOSA-N |
| SMILES | C1CC1NC2=C3C(=NC(=N2)N)N(C=N3)[C@@H]4C[C@@H](C=C4)CO |
Computed by PubChem (NCBI)
Synonyms:
abacavir, (1S,4R)-4-[2-Amino-6-(cyclopropylamino)-9H-purin-9-yl]-2-cyclopentene-1-methanol, Avacavir, [(1s,4r)-4-[2-amino-6-(cyclopropylamino)purin-9-yl]-1-cyclopent-2-enyl]methanol, (1S,4R)-4-(2-amino-6-(cyclopropylamino)-9H-purin-9-yl)-2-cyclopentene-1-methanol, abacavirum, ((1S,4R)-4-(2-amino-6-(cyclopropylamino)purin-9-yl)-1-cyclopent-2-enyl)methanol, (+)-abacavir sulfate, (1R,4S)-abacavir sulfate, Ziagen