Afatinib, 96%
cas: 850140-72-6 — see every product listed under this CAS number, including other names
Afatinib, 96% (CAS 850140-72-6) is a chemical reagent available from Chemat. Available pack sizes: 1g, 250MG. Offered by: Thermo Scientific (Acros).
| brand | Thermo Scientific (Acros) |
|---|---|
| catalog number | 465640010 |
| cas | 850140-72-6 |
| size | 1g |
| availability | availability |
Documents:
Safety Data Sheet (MSDS)
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Available pack sizes
| brand | size | price | |
|---|---|---|---|
| Thermo Scientific (Acros) | 1g | 1461.06 Pln | |
| Thermo Scientific (Acros) | 250MG | 449.90 Pln |
properties
| delivery time | 2-3 weeks |
|---|---|
| category | Chemicals |
| purity | 96% |
Afatinib is a quinazoline compound having a 3-chloro-4-fluoroanilino group at the 4-position, a 4-dimethylamino-trans-but-2-enamido group at the 6-position, and an (S)-tetrahydrofuran-3-yloxy group at the 7-position. Used (as its dimaleate salt) for the first-line treatment of patients with metastatic non-small cell lung cancer. It has a role as an antineoplastic agent and a tyrosine kinase inhibitor. It is a secondary carboxamide, a member of furans, an aromatic ether, an organofluorine compound, a member of quinazolines, a tertiary amino compound, an enamide and a member of monochlorobenzenes.
Source: ChEBI
| Molecular formula | C24H25ClFN5O3 |
|---|---|
| Molecular weight | 485.9 g/mol |
| IUPAC name | (E)-N-[4-(3-chloro-4-fluoroanilino)-7-[(3S)-oxolan-3-yl]oxyquinazolin-6-yl]-4-(dimethylamino)but-2-enamide |
| InChIKey | ULXXDDBFHOBEHA-CWDCEQMOSA-N |
| SMILES | CN(C)C/C=C/C(=O)NC1=C(C=C2C(=C1)C(=NC=N2)NC3=CC(=C(C=C3)F)Cl)O[C@H]4CCOC4 |
Computed by PubChem (NCBI)