Afatinib, 99.93%

cas: 850140-72-6 — see every product listed under this CAS number, including other names

Afatinib, 99.93% (CAS 850140-72-6) is a chemical reagent available from Chemat. Available pack sizes: 5 mg, 25 mg, 100 mg, 50 mg, 10mM/1mL, 10 mg, 200 mg, 500 mg. Offered by: MedChemExpress.

brandMedChemExpress
catalog numberHY-10261-5 mg
cas850140-72-6
size5 mg
availability In stock
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Available pack sizes

brand size price
MedChemExpress 5 mg 301.12 Pln
MedChemExpress 25 mg 607.62 Pln
MedChemExpress 100 mg 983.78 Pln
MedChemExpress 50 mg 811.96 Pln
MedChemExpress 10mM/1mL 435.79 Pln
MedChemExpress 10 mg 407.93 Pln
MedChemExpress 200 mg 1215.98 Pln
MedChemExpress 500 mg 1945.09 Pln

properties

delivery time 1-2 weeks
purity99.93%
Structural formula: {0} (CAS {1})

Afatinib is a quinazoline compound having a 3-chloro-4-fluoroanilino group at the 4-position, a 4-dimethylamino-trans-but-2-enamido group at the 6-position, and an (S)-tetrahydrofuran-3-yloxy group at the 7-position. Used (as its dimaleate salt) for the first-line treatment of patients with metastatic non-small cell lung cancer. It has a role as an antineoplastic agent and a tyrosine kinase inhibitor. It is a secondary carboxamide, a member of furans, an aromatic ether, an organofluorine compound, a member of quinazolines, a tertiary amino compound, an enamide and a member of monochlorobenzenes.

Source: ChEBI

Identity
Molecular formulaC24H25ClFN5O3
Molecular weight485.9 g/mol
IUPAC name(E)-N-[4-(3-chloro-4-fluoroanilino)-7-[(3S)-oxolan-3-yl]oxyquinazolin-6-yl]-4-(dimethylamino)but-2-enamide
InChIKeyULXXDDBFHOBEHA-CWDCEQMOSA-N
SMILESCN(C)C/C=C/C(=O)NC1=C(C=C2C(=C1)C(=NC=N2)NC3=CC(=C(C=C3)F)Cl)O[C@H]4CCOC4

Computed by PubChem (NCBI)

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