CHM-1
cas: 154554-41-3 — see every product listed under this CAS number, including other names
CHM-1 (CAS 154554-41-3) is a chemical reagent available from Chemat. Available pack sizes: 25mg. Offered by: TRC.
| brand | TRC |
|---|---|
| catalog number | TRC-C381168-25MG |
| cas | 154554-41-3 |
| size | 25mg |
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Available pack sizes
| brand | size | price | |
|---|---|---|---|
| TRC | 25mg | price on request |
properties
| purity | No data |
|---|---|
| delivery time | To be confirmed by Chemat |
CHM-1, a microtubule-destabilizing agent, inhibits tubulin polymerization. CHM-1 is a potent and selective antimitotic antitumor activity against human hepatocellular carcinoma. CHM-1 induces growth inhibition and apoptosis via G2-M phase arrest in human hepatocellular carcinoma cells by activation of Cdc2 kinase activity. (MedChemExpress).
Source: ChEBI
| Molecular formula | C16H10FNO3 |
|---|---|
| Molecular weight | 283.25 g/mol |
| IUPAC name | 6-(2-fluorophenyl)-5H-[1,3]dioxolo[4,5-g]quinolin-8-one |
| InChIKey | ZMYDAPJHGNEFGQ-UHFFFAOYSA-N |
| SMILES | C1OC2=C(O1)C=C3C(=C2)C(=O)C=C(N3)C4=CC=CC=C4F |
Computed by PubChem (NCBI)
Synonyms:
6-(2-Fluorophenyl)-1,3-dioxolo[4,5-g]quinolin-8(5H)-one, 6-(2-fluorophenyl)-5H-[1,3]dioxolo[4,5-g]quinolin-8-one, 6-(2-Fluorophenyl)-5H-(1,3)dioxolo(4,5-g)quinolin-8-one, 6-(2-Fluorophenyl)-1,3-dioxolo(4,5-g)quinolin-8(5H)-one, 6-(2-Fluorophenyl)[1,3]dioxolo[4,5-G]quinolin-8(5h)-One, 6-(2-fluorophenyl)-[1,3]dioxolo[4,5-g]quinolin-8(5H)-one, 1,5-g]quinolin-8(5H)-one, 6-(2-fluorophenyl)-, 2-(2-fluorophenyl)-6,7-methylenedioxy-2-4-quinolone hydrate, NSC 656158, 1,3-Dioxolo[4,5-g]quinolin-8(5H)-one, 6-(2-fluorophenyl)-, Neuro_000375