Products 477-30-5
CAS 477-30-5 appears in our catalog under these names: Colcemid, Demecolcine, Demecolcine, >95% (HPLC), Colcemid, 98+% , Demecolcine, 98.00%. Offered by: GLPBio, Chemat Brand, TRC, Thermo Scientific (Alfa Aesar), Biosynth. Available pack sizes: 5mg, on request, 10mg, 1mg, 10mM (in 1ml dmso), 50mg, 25mg, 100ML.
(-)-demecolcine is a secondary amino compound that is (S)-colchicine in which the N-acetyl group is replaced by an N-methyl group. Isolable from the autumn crocus, Colchicum autumnale, it is less toxic than colchicine and is used as an antineoplastic. It has a role as an antineoplastic agent and a microtubule-destabilising agent. It is an alkaloid and a secondary amino compound.
Source: ChEBI
| Molecular formula | C21H25NO5 |
|---|---|
| Molecular weight | 371.4 g/mol |
| IUPAC name | (7S)-1,2,3,10-tetramethoxy-7-(methylamino)-6,7-dihydro-5H-benzo[a]heptalen-9-one |
| InChIKey | NNJPGOLRFBJNIW-HNNXBMFYSA-N |
| SMILES | CN[C@H]1CCC2=CC(=C(C(=C2C3=CC=C(C(=O)C=C13)OC)OC)OC)OC |
Computed by PubChem (NCBI)
Synonyms:
Demecolcine, colcemid, Demecolcin, Desmecolcine, Kolchamin, Kolkamin, Omaine, Omain, Santavy's substance F, Methylcolchicine