Crizotinib 98%

cas: 877399-52-5 — see every product listed under this CAS number, including other names

Crizotinib 98% (CAS 877399-52-5) is a chemical reagent available from Chemat. Available pack sizes: 1mg, 10mg, 25mg, 100mg, 250mg, 1g, 5g, 25g. Offered by: Ambeed.

brandAmbeed
catalog numberA106537-1mg
cas877399-52-5
size1mg
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Available pack sizes

brand size price
Ambeed 1mg 175.69 Pln
Ambeed 10mg 197.94 Pln
Ambeed 25mg 220.19 Pln
Ambeed 100mg 253.56 Pln
Ambeed 250mg 292.50 Pln
Ambeed 1g 526.12 Pln
Ambeed 5g 1093.50 Pln
Ambeed 25g 3641.12 Pln

properties

purity98%
delivery time 1-2 weeks
ambeed catalog no.A106537
Structural formula: {0} (CAS {1})

Crizotinib is a 3-[1-(2,6-dichloro-3-fluorophenyl)ethoxy]-5-[1-(piperidin-4-yl)pyrazol-4-yl]pyridin-2-amine that has R configuration at the chiral centre. The active enantiomer, it acts as a kinase inhibitor and is used for the treatment of patients with locally advanced or metastatic non-small cell lung cancer (NSCLC). It has a role as an antineoplastic agent, a biomarker and an EC 2.7.10.1 (receptor protein-tyrosine kinase) inhibitor. It is an enantiomer of an ent-crizotinib.

Source: ChEBI

Identity
Molecular formulaC21H22Cl2FN5O
Molecular weight450.3 g/mol
IUPAC name3-[(1R)-1-(2,6-dichloro-3-fluorophenyl)ethoxy]-5-(1-piperidin-4-ylpyrazol-4-yl)pyridin-2-amine
InChIKeyKTEIFNKAUNYNJU-GFCCVEGCSA-N
SMILESC[C@H](C1=C(C=CC(=C1Cl)F)Cl)OC2=C(N=CC(=C2)C3=CN(N=C3)C4CCNCC4)N

Computed by PubChem (NCBI)

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