Cyclo(his–pro) (Cyclo(histidyl–proline))

cas: 53109-32-3 — see every product listed under this CAS number, including other names

Cyclo(his–pro) (Cyclo(histidyl–proline)) (CAS 53109-32-3) is a chemical reagent available from Chemat. Available pack sizes: 100mg, 25mg, 50mg. Offered by: GLPBio.

brandGLPBio
catalog numberGC30806-100
cas53109-32-3
size100mg
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Available pack sizes

brand size price
GLPBio 100mg 1444.21 Pln
GLPBio 25mg 793.62 Pln
GLPBio 50mg 1079.13 Pln

properties

purityNo data
delivery timeTo be confirmed by Chemat
Structural formula: {0} (CAS {1})

Cyclo(L-His-L-Pro) is a homodetic cyclic peptide resulting from the formal condensation of both the amino and acid groups of L-histidine with the acid and amino groups of L-proline. It is a metabolite of thyrotropin-releasing hormone (TRH). It has a role as a dopamine uptake inhibitor, an anti-inflammatory agent and a human blood serum metabolite. It is a homodetic cyclic peptide, a member of imidazoles, a dipeptide and a pyrrolopyrazine. It is functionally related to a L-histidine and a L-proline.

Source: ChEBI

Identity
Molecular formulaC11H14N4O2
Molecular weight234.25 g/mol
IUPAC name(3S,8aS)-3-(1H-imidazol-5-ylmethyl)-2,3,6,7,8,8a-hexahydropyrrolo[1,2-a]pyrazine-1,4-dione
InChIKeyNAKUGCPAQTUSBE-IUCAKERBSA-N
SMILESC1C[C@H]2C(=O)N[C@H](C(=O)N2C1)CC3=CN=CN3

Computed by PubChem (NCBI)

Synonyms: Cyclo(his-pro), Cyclo(L-His-L-Pro), L-His-L-Pro-DKP, L,L-cyclo(histidylprolyl), (3S,8aS)-3-(1H-Imidazol-4-ylmethyl)hexahydropyrrolo[1,2-a]pyrazine-1,4-dione, (3S,8aS)-3-[(1H-imidazol-5-yl)methyl]hexahydropyrrolo[1,2-a]pyrazine-1,4-dione, (3S,8aS)-3-((1H-imidazol-5-yl)methyl)-octahydropyrrolo(1,2-a)pyrazine-1,4-dione, (3S,8aS)-3-((1H-imidazol-5-yl)methyl)hexahydropyrrolo(1,2-a)pyrazine-1,4-dione, (3S,8aS)-3-(1H-Imidazol-4-ylmethyl)hexahydropyrrolo(1,2-a)pyrazine-1,4-dione, (3S,8aS)-3-[(1H-imidazol-5-yl)methyl]-octahydropyrrolo[1,2-a]pyrazine-1,4-dione
Related forms of this compound
(3R,8aS)-3-(1H-imidazol-5-ylmethyl)-2,3,6,7,8,8a-hexahydropyrrolo[1,2-a]pyrazine-1,4-dione C11H14N4O2
Isomers (same molecular formula)
tert-butyl N-pyrazolo[1,5-a]pyrimidin-2-ylcarbamate C11H14N4O2
2,2-dimethyl-N-(4-oxo-3,7-dihydropyrrolo[2,3-d]pyrimidin-2-yl)propanamide C11H14N4O2
[(2S,5R)-5-(4-aminopyrrolo[2,3-d]pyrimidin-7-yl)oxolan-2-yl]methanol C11H14N4O2
tert-butyl N-pyrazolo[1,5-a]pyrimidin-3-ylcarbamate C11H14N4O2
[4-([1,3]oxazolo[4,5-b]pyridin-2-yl)morpholin-2-yl]methanamine C11H14N4O2
tert-butyl N-(6-amino-5-cyano-3-pyridinyl)carbamate C11H14N4O2
3-(1-ethyl-3,5-dimethylpyrazol-4-yl)-1H-pyrazole-5-carboxylic acid C11H14N4O2
1-methyl-3-(1,3,5-trimethylpyrazol-4-yl)pyrazole-5-carboxylic acid C11H14N4O2
4-[(E)-3-(1-methylpyrazol-4-yl)prop-2-enoyl]piperazin-2-one C11H14N4O2
tert-butyl N-(5H-pyrrolo[3,2-d]pyrimidin-4-yl)carbamate C11H14N4O2
3-(7-propan-2-yl-[1,2,4]triazolo[1,5-a]pyrimidin-2-yl)propanoic acid C11H14N4O2

Also listed as

Protirelin EP Impurity E Chemat Brand CAS 53109-32-3
Cyclo(L-histidyl-L-proline) TRC CAS 53109-32-3
Cyclo(his-pro), 98% AmBeed CAS 53109-32-3
Cyclo(his-pro)/ 99.87% (existing batch purity) TargetMol CAS 53109-32-3
Cyclo(L-His-L-Pro) Biosynth CAS 53109-32-3
(3S,8aS)-Hexahydro-3-(1H-imidazol-4-ylmethyl)pyrrolo[1,2-a]pyrazine-1,4-dione, 99.87% ,, 99.87% , Chemat CAS 53109-32-3
Cyclo(his-pro), 99.41% MedChemExpress CAS 53109-32-3
Cyclo(L-His-L-Pro), 50 mg Roth CAS 53109-32-3
Cyclo(L-His-L-Pro), 100 mg Roth CAS 53109-32-3
Cyclo(L-His-L-Pro), 250 mg Roth CAS 53109-32-3
(3S,8aS)-Hexahydro-3-(1H-imidazol-4-ylmethyl)pyrrolo[1,2-a]pyrazine-1,4-dione, ≥98% Chemat CAS 53109-32-3