Products 53109-32-3
CAS 53109-32-3 appears in our catalog under these names: Protirelin EP Impurity E, Cyclo(L-histidyl-L-proline), Cyclo(his-pro), 98%, Cyclo(his-pro)/ 99.87% (existing batch purity), Cyclo(his–pro) (Cyclo(histidyl–proline)). Offered by: Chemat Brand, TRC, AmBeed, TargetMol, GLPBio. Available pack sizes: on request, 500mg, 50mg, 1mg, 5mg, 10mg, 25mg, 100mg.
Cyclo(L-His-L-Pro) is a homodetic cyclic peptide resulting from the formal condensation of both the amino and acid groups of L-histidine with the acid and amino groups of L-proline. It is a metabolite of thyrotropin-releasing hormone (TRH). It has a role as a dopamine uptake inhibitor, an anti-inflammatory agent and a human blood serum metabolite. It is a homodetic cyclic peptide, a member of imidazoles, a dipeptide and a pyrrolopyrazine. It is functionally related to a L-histidine and a L-proline.
Source: ChEBI
| Molecular formula | C11H14N4O2 |
|---|---|
| Molecular weight | 234.25 g/mol |
| IUPAC name | (3S,8aS)-3-(1H-imidazol-5-ylmethyl)-2,3,6,7,8,8a-hexahydropyrrolo[1,2-a]pyrazine-1,4-dione |
| InChIKey | NAKUGCPAQTUSBE-IUCAKERBSA-N |
| SMILES | C1C[C@H]2C(=O)N[C@H](C(=O)N2C1)CC3=CN=CN3 |
Computed by PubChem (NCBI)
Synonyms:
Cyclo(his-pro), Cyclo(L-His-L-Pro), L-His-L-Pro-DKP, L,L-cyclo(histidylprolyl), (3S,8aS)-3-(1H-Imidazol-4-ylmethyl)hexahydropyrrolo[1,2-a]pyrazine-1,4-dione, (3S,8aS)-3-[(1H-imidazol-5-yl)methyl]hexahydropyrrolo[1,2-a]pyrazine-1,4-dione, (3S,8aS)-3-((1H-imidazol-5-yl)methyl)-octahydropyrrolo(1,2-a)pyrazine-1,4-dione, (3S,8aS)-3-((1H-imidazol-5-yl)methyl)hexahydropyrrolo(1,2-a)pyrazine-1,4-dione, (3S,8aS)-3-(1H-Imidazol-4-ylmethyl)hexahydropyrrolo(1,2-a)pyrazine-1,4-dione, (3S,8aS)-3-[(1H-imidazol-5-yl)methyl]-octahydropyrrolo[1,2-a]pyrazine-1,4-dione