Eltrombopag

cas: 496775-61-2 — see every product listed under this CAS number, including other names

Eltrombopag (CAS 496775-61-2) is a chemical reagent available from Chemat. Available pack sizes: on request, 10mg, 100mg, 200mg, 25mg, 10mM (in 1ml dmso), 50mg, 500mg. Offered by: Chemat Brand, GLPBio, Biosynth.

brandChemat Brand
catalog numberULE481
cas496775-61-2
sizeon request
availability Do potwierdzenia przez Chemat|To be confirmed by Chemat
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Available pack sizes

brand size price
Chemat Brand on request price on request
GLPBio 10mg 667.25 Pln
GLPBio 100mg 1191.46 Pln
GLPBio 200mg 1495.70 Pln
GLPBio 25mg 826.38 Pln
GLPBio 10mM (in 1ml dmso) 774.90 Pln
GLPBio 50mg 1065.09 Pln
GLPBio 500mg 1893.54 Pln
Biosynth 1g price on request
Biosynth 0,5g price on request
Biosynth 2g price on request
Biosynth 5g price on request
Biosynth 10g price on request

properties

purityNo data
categoryChemicals
delivery timeTo be confirmed by Chemat
Structural formula: {0} (CAS {1})

Eltrombopag is a hydrazine in which each nitrogen atom is substituted, one by a 3'-carboxy-2-hydroxy[1,1'-biphenyl]-3-yl group and the other by a 1-(3,4-dimethylphenyl)-3-methyl-5-oxo-1,5-dihydro-4H-pyrazol-4-ylidene group. A small molecule agonist of the c-mpl (TpoR) receptor (the physiological target of the hormone thrombopoietin), it has been developed as a medication for conditions that lead to thrombocytopenia (abnormally low platelet counts). It has a role as a xenobiotic and a thrombopoietin receptor agonist. It is a member of benzoic acids, a member of hydrazines and a member of pyrazoles.

Source: ChEBI

Identity
Molecular formulaC25H22N4O4
Molecular weight442.5 g/mol
IUPAC name3-[3-[[2-(3,4-dimethylphenyl)-5-methyl-3-oxo-1H-pyrazol-4-yl]diazenyl]-2-hydroxyphenyl]benzoic acid
InChIKeySVOQIEJWJCQGDQ-UHFFFAOYSA-N
SMILESCC1=C(C=C(C=C1)N2C(=O)C(=C(N2)C)N=NC3=CC=CC(=C3O)C4=CC(=CC=C4)C(=O)O)C

Computed by PubChem (NCBI)

Synonyms: Eltrombopag, Eltrombopag [INN], Eltrombopag-Isomer, (E)-Eltrombopag, (ZE)-Eltrombopag, Eltrombopag free base, 496775-61-2 (free base), Eltrombopag (Standard), ELTROMBOPAG [MI], (E/Z)-Eltrombopag 13C
Related forms of this compound
3-[3-[[2-(3,4-dimethylphenyl)-5-methyl-3-oxo-1H-pyrazol-4-yl]diazenyl]-2-hydroxyphenyl]benzoic acid C25H22N4O4
3-[3-[[2-(3,4-dimethylphenyl)-5-(113C)methyl-3-oxo-(3,4,5-13C3)1H-pyrazol-4-yl]diazenyl]-2-hydroxyphenyl](13C)benzoic acid C25H22N4O4
3-[3-[[2-(3,4-dimethylphenyl)-5-methyl-3-oxo-1H-pyrazol-4-yl]diazenyl]-2-hydroxyphenyl]benzoic acid C25H22N4O4
Isomers (same molecular formula)
3-[3-[[1-(3,4-dimethylphenyl)-3-methyl-5-oxo-4H-pyrazol-4-yl]diazenyl]-2-hydroxyphenyl]benzoic acid C25H22N4O4

Also listed as

Eltrombopag, min. 95 %, 2 g Roth CAS 496775-61-2
Eltrombopag, >95% (HPLC) TRC CAS 496775-61-2
Eltrombopag/ 99.73% (existing batch purity) TargetMol CAS 496775-61-2
Eltrombopag - Bio-X â„¢ Biosynth CAS 496775-61-2
Eltrombopag 99+% Ambeed CAS 496775-61-2
3'-[(2Z)-2-[1-(3,4-Dimethylphenyl)-1,5-dihydro-3-methyl-5-oxo-4H-pyrazol-4-ylidene]hydrazinyl]-2'-hydroxy[1,1'-biphenyl]-3-carboxylic acid, 99+%, 99+% Chemat CAS 496775-61-2
Eltrombopag, 99.94% MedChemExpress CAS 496775-61-2
Eltrombopag (Standard) MedChemExpress CAS 496775-61-2
Eltrombopag, min. 95 %, 500 mg Roth CAS 496775-61-2
Eltrombopag, min. 95 %, 1 g Roth CAS 496775-61-2
Eltrombopag, BioScience Grade, 10 mg Roth CAS 496775-61-2