Products 1807882-48-9

CAS 1807882-48-9 is the registry number for Eltrombopag-Isomer, 98%. Offered by: AmBeed. Available pack sizes: 1g.

Eltrombopag-Isomer, 98%
AmBeed
  • size: 1g
  • Variants: 1
from 6833.89
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Structural formula: {0} (CAS {1})

Eltrombopag is a hydrazine in which each nitrogen atom is substituted, one by a 3'-carboxy-2-hydroxy[1,1'-biphenyl]-3-yl group and the other by a 1-(3,4-dimethylphenyl)-3-methyl-5-oxo-1,5-dihydro-4H-pyrazol-4-ylidene group. A small molecule agonist of the c-mpl (TpoR) receptor (the physiological target of the hormone thrombopoietin), it has been developed as a medication for conditions that lead to thrombocytopenia (abnormally low platelet counts). It has a role as a xenobiotic and a thrombopoietin receptor agonist. It is a member of benzoic acids, a member of hydrazines and a member of pyrazoles.

Source: ChEBI

Identity
Molecular formulaC25H22N4O4
Molecular weight442.5 g/mol
IUPAC name3-[3-[[2-(3,4-dimethylphenyl)-5-methyl-3-oxo-1H-pyrazol-4-yl]diazenyl]-2-hydroxyphenyl]benzoic acid
InChIKeySVOQIEJWJCQGDQ-UHFFFAOYSA-N
SMILESCC1=C(C=C(C=C1)N2C(=O)C(=C(N2)C)N=NC3=CC=CC(=C3O)C4=CC(=CC=C4)C(=O)O)C

Computed by PubChem (NCBI)

Synonyms: Eltrombopag, Eltrombopag [INN], Eltrombopag-Isomer, (E)-Eltrombopag, (ZE)-Eltrombopag, Eltrombopag free base, 496775-61-2 (free base), Eltrombopag, (E)-, Eltrombopag (Standard), ELTROMBOPAG [MI]
Related forms of this compound
3-[3-[[2-(3,4-dimethylphenyl)-5-methyl-3-oxo-1H-pyrazol-4-yl]diazenyl]-2-hydroxyphenyl]benzoic acid C25H22N4O4
3-[3-[[2-(3,4-dimethylphenyl)-5-methyl-3-oxo-1H-pyrazol-4-yl]diazenyl]-2-hydroxyphenyl]benzoic acid C25H22N4O4
3-[3-[[2-(3,4-dimethylphenyl)-5-(113C)methyl-3-oxo-(3,4,5-13C3)1H-pyrazol-4-yl]diazenyl]-2-hydroxyphenyl](13C)benzoic acid C25H22N4O4
Isomers (same molecular formula)
3-[3-[[1-(3,4-dimethylphenyl)-3-methyl-5-oxo-4H-pyrazol-4-yl]diazenyl]-2-hydroxyphenyl]benzoic acid C25H22N4O4