GSK J4
cas: 1373423-53-0 — see every product listed under this CAS number, including other names
GSK J4 (CAS 1373423-53-0) is a chemical reagent available from Chemat. Available pack sizes: 100mg, 1g. Offered by: TRC, Biosynth.
| brand | TRC |
|---|---|
| catalog number | TRC-G797555-100MG |
| cas | 1373423-53-0 |
| size | 100mg |
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Available pack sizes
| brand | size | price | |
|---|---|---|---|
| TRC | 100mg | price on request | |
| Biosynth | 1g | price on request |
properties
| purity | No data |
|---|---|
| delivery time | To be confirmed by Chemat |
GSK-J4 is a member of the class of aminopyrimidines that is pyrimidine substituted by pyridin-2-yl, 3-ethoxy-3-oxopropylamino, and 1,2,4,5-tetrahydro-3H-3-benzazepin-3-yl groups at positions 2, 4, and 6, respectively. It is an inhibitor of the histone demethylase JMJD3/UTX. It has a role as a ferroptosis inducer, an EC 1.14.11.68 ([histone H3]-trimethyl-L-lysine(27) demethylase) inhibitor, an antineoplastic agent and a prodrug. It is an ethyl ester, a member of pyridines, a benzazepine, an aminopyrimidine, a secondary amino compound and a tertiary amino compound. It is functionally related to a GSK-J1.
Source: ChEBI
| Molecular formula | C24H27N5O2 |
|---|---|
| Molecular weight | 417.5 g/mol |
| IUPAC name | ethyl 3-[[2-pyridin-2-yl-6-(1,2,4,5-tetrahydro-3-benzazepin-3-yl)pyrimidin-4-yl]amino]propanoate |
| InChIKey | WBKCKEHGXNWYMO-UHFFFAOYSA-N |
| SMILES | CCOC(=O)CCNC1=CC(=NC(=N1)C2=CC=CC=N2)N3CCC4=CC=CC=C4CC3 |
Computed by PubChem (NCBI)