HMN–214
cas: 173529-46-9 — see every product listed under this CAS number, including other names
HMN–214 (CAS 173529-46-9) is a chemical reagent available from Chemat. Available pack sizes: 10mg, 5mg, 10mM (in 1ml dmso), 50mg. Offered by: GLPBio.
| brand | GLPBio |
|---|---|
| catalog number | GC13928-10 |
| cas | 173529-46-9 |
| size | 10mg |
Need more information?
Ask us about this product — we're happy to help.
Available pack sizes
| brand | size | price | |
|---|---|---|---|
| GLPBio | 10mg | 915.31 Pln | |
| GLPBio | 5mg | 793.62 Pln | |
| GLPBio | 10mM (in 1ml dmso) | 910.63 Pln | |
| GLPBio | 50mg | 2225.85 Pln |
properties
| purity | No data |
|---|---|
| delivery time | To be confirmed by Chemat |
HMN-214 is an N-sulfonylcarboxamide that is N-[(4-methoxyphenyl)sulfonyl]acetamide in which the hydrogen of the NH group is substituted by a 2-[(E)-2-(1-oxidopyridin-4-yl)ethenyl]phenyl group. It is a potent inhibitor of polo-like kinase 1 (PLK1) that exhibits antineoplastic activity. It has a role as an EC 2.7.11.21 (polo kinase) inhibitor, an antineoplastic agent, a prodrug and an apoptosis inducer. It is a monomethoxybenzene, a member of pyridine N-oxides, an olefinic compound and a N-sulfonylcarboxamide.
Source: ChEBI
| Molecular formula | C22H20N2O5S |
|---|---|
| Molecular weight | 424.5 g/mol |
| IUPAC name | N-(4-methoxyphenyl)sulfonyl-N-[2-[(E)-2-(1-oxidopyridin-1-ium-4-yl)ethenyl]phenyl]acetamide |
| InChIKey | OCKHRKSTDPOHEN-BQYQJAHWSA-N |
| SMILES | CC(=O)N(C1=CC=CC=C1/C=C/C2=CC=[N+](C=C2)[O-])S(=O)(=O)C3=CC=C(C=C3)OC |
Computed by PubChem (NCBI)