Products 173529-46-9
CAS 173529-46-9 appears in our catalog under these names: HMN-214/ 99.28% (existing batch purity), HMN–214, HMN-214 98%, HMN-214, 98%, 98%, HMN-214, 99.94%. Offered by: TargetMol, GLPBio, Ambeed, Chemat, MedChemExpress. Available pack sizes: 1mg, 2mg, 5mg, 10mg, 25mg, 50mg, 100mg, 500mg.
HMN-214 is an N-sulfonylcarboxamide that is N-[(4-methoxyphenyl)sulfonyl]acetamide in which the hydrogen of the NH group is substituted by a 2-[(E)-2-(1-oxidopyridin-4-yl)ethenyl]phenyl group. It is a potent inhibitor of polo-like kinase 1 (PLK1) that exhibits antineoplastic activity. It has a role as an EC 2.7.11.21 (polo kinase) inhibitor, an antineoplastic agent, a prodrug and an apoptosis inducer. It is a monomethoxybenzene, a member of pyridine N-oxides, an olefinic compound and a N-sulfonylcarboxamide.
Source: ChEBI
| Molecular formula | C22H20N2O5S |
|---|---|
| Molecular weight | 424.5 g/mol |
| IUPAC name | N-(4-methoxyphenyl)sulfonyl-N-[2-[(E)-2-(1-oxidopyridin-1-ium-4-yl)ethenyl]phenyl]acetamide |
| InChIKey | OCKHRKSTDPOHEN-BQYQJAHWSA-N |
| SMILES | CC(=O)N(C1=CC=CC=C1/C=C/C2=CC=[N+](C=C2)[O-])S(=O)(=O)C3=CC=C(C=C3)OC |
Computed by PubChem (NCBI)