LLY-283, 98.93%
cas: 2040291-27-6 — see every product listed under this CAS number, including other names
LLY-283, 98.93% (CAS 2040291-27-6) is a chemical reagent available from Chemat. Available pack sizes: 50 mg, 25 mg, 10mM/1mL, 10 mg, 100 mg, 5 mg. Offered by: MedChemExpress.
| brand | MedChemExpress |
|---|---|
| catalog number | HY-107777-50 mg |
| cas | 2040291-27-6 |
| size | 50 mg |
| availability | In stock |
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Available pack sizes
| brand | size | price | |
|---|---|---|---|
| MedChemExpress | 50 mg | 2971.42 Pln | |
| MedChemExpress | 25 mg | 1703.60 Pln | |
| MedChemExpress | 10mM/1mL | 644.77 Pln | |
| MedChemExpress | 10 mg | 909.48 Pln | |
| MedChemExpress | 100 mg | 5079.79 Pln | |
| MedChemExpress | 5 mg | 593.69 Pln |
properties
| delivery time | 1-2 weeks |
|---|---|
| purity | 98.93% |
LLY283 is lLY-283 is a novel and selective inhibitor of protein arginine methyltransferase 5 (PRMT5). LLY-283 inhibits PRMT5 enzymatic activity in vitro and in cells with IC50 of 22 nM and 25 nM, respectively. LLY-283 shows antitumor activity.
Source: ChEBI
| Molecular formula | C17H18N4O4 |
|---|---|
| Molecular weight | 342.35 g/mol |
| IUPAC name | (2R,3R,4S,5R)-2-(4-aminopyrrolo[2,3-d]pyrimidin-7-yl)-5-[(R)-hydroxy(phenyl)methyl]oxolane-3,4-diol |
| InChIKey | WWOOWAHTEXIWBO-QFRSUPTLSA-N |
| SMILES | C1=CC=C(C=C1)[C@H]([C@@H]2[C@H]([C@H]([C@@H](O2)N3C=CC4=C(N=CN=C43)N)O)O)O |
Computed by PubChem (NCBI)