Products 2040291-27-6
CAS 2040291-27-6 appears in our catalog under these names: LLY-283, LLY-283/ 98.79% (existing batch purity), LLY 283, LLY-283 99%, (2R,3R,4S,5R)-2-(4-Amino-7H-pyrrolo[2,3-d]pyrimidin-7-yl)-5-((R)-hydroxy(phenyl)methyl)tetrahydrofuran-3,4-diol, 99%, 99%. Offered by: Chemat Brand, TargetMol, Biosynth, Ambeed, Chemat. Available pack sizes: on request, 1mg, 5mg, 100mg, 10mg, 25mg, 50mg, 250mg.
LLY283 is lLY-283 is a novel and selective inhibitor of protein arginine methyltransferase 5 (PRMT5). LLY-283 inhibits PRMT5 enzymatic activity in vitro and in cells with IC50 of 22 nM and 25 nM, respectively. LLY-283 shows antitumor activity.
Source: ChEBI
| Molecular formula | C17H18N4O4 |
|---|---|
| Molecular weight | 342.35 g/mol |
| IUPAC name | (2R,3R,4S,5R)-2-(4-aminopyrrolo[2,3-d]pyrimidin-7-yl)-5-[(R)-hydroxy(phenyl)methyl]oxolane-3,4-diol |
| InChIKey | WWOOWAHTEXIWBO-QFRSUPTLSA-N |
| SMILES | C1=CC=C(C=C1)[C@H]([C@@H]2[C@H]([C@H]([C@@H](O2)N3C=CC4=C(N=CN=C43)N)O)O)O |
Computed by PubChem (NCBI)