LLY-283

cas: 2040291-27-6 — see every product listed under this CAS number, including other names

LLY-283 (CAS 2040291-27-6) is a chemical reagent available from Chemat. Available pack sizes: on request. Offered by: Chemat Brand.

brandChemat Brand
catalog numberULK031050
cas2040291-27-6
sizeon request
availability Do potwierdzenia przez Chemat|To be confirmed by Chemat
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purityNo data
categoryChemicals
delivery timeTo be confirmed by Chemat
Structural formula: {0} (CAS {1})

LLY283 is lLY-283 is a novel and selective inhibitor of protein arginine methyltransferase 5 (PRMT5). LLY-283 inhibits PRMT5 enzymatic activity in vitro and in cells with IC50 of 22 nM and 25 nM, respectively. LLY-283 shows antitumor activity.

Source: ChEBI

Identity
Molecular formulaC17H18N4O4
Molecular weight342.35 g/mol
IUPAC name(2R,3R,4S,5R)-2-(4-aminopyrrolo[2,3-d]pyrimidin-7-yl)-5-[(R)-hydroxy(phenyl)methyl]oxolane-3,4-diol
InChIKeyWWOOWAHTEXIWBO-QFRSUPTLSA-N
SMILESC1=CC=C(C=C1)[C@H]([C@@H]2[C@H]([C@H]([C@@H](O2)N3C=CC4=C(N=CN=C43)N)O)O)O

Computed by PubChem (NCBI)

Synonyms: 7-[(5R)-5-C-phenyl-beta-D-ribofuranosyl]-7H-pyrrolo[2,3-d]pyrimidin-4-amine, orb1707062, 7-[(5R)-5-CPhenyl-|A-D-ribofuranosyl]-7H-pyrrolo[2,3-d]pyrimidin-4-amine
Isomers (same molecular formula)
2-[(2-aminoacetyl)amino]-N-(4-nitrophenyl)-3-phenylpropanamide C17H18N4O4
2-(2,6-dioxopiperidin-3-yl)-4-[[(3R)-pyrrolidin-3-yl]amino]isoindole-1,3-dione C17H18N4O4
ethyl 2-(2-ethoxyphenyl)-5-methyl-4-oxo-3H-imidazo[5,1-f][1,2,4]triazine-7-carboxylate C17H18N4O4

Also listed as

LLY-283/ 98.79% (existing batch purity) TargetMol CAS 2040291-27-6
LLY 283 Biosynth CAS 2040291-27-6
LLY-283 99% Ambeed CAS 2040291-27-6
(2R,3R,4S,5R)-2-(4-Amino-7H-pyrrolo[2,3-d]pyrimidin-7-yl)-5-((R)-hydroxy(phenyl)methyl)tetrahydrofuran-3,4-diol, 99%, 99% Chemat CAS 2040291-27-6
LLY-283, 98.93% MedChemExpress CAS 2040291-27-6