RK–24466 (KIN 001–51)

cas: 213743-31-8 — see every product listed under this CAS number, including other names

RK–24466 (KIN 001–51) (CAS 213743-31-8) is a chemical reagent available from Chemat. Available pack sizes: 1mg, 10mg, 25mg, 5mg, 10mM (in 1ml dmso). Offered by: GLPBio.

brandGLPBio
catalog numberGC31701-1
cas213743-31-8
size1mg
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Available pack sizes

brand size price
GLPBio 1mg 667.25 Pln
GLPBio 10mg 1467.61 Pln
GLPBio 25mg 2207.13 Pln
GLPBio 5mg 1046.37 Pln
GLPBio 10mM (in 1ml dmso) 1111.89 Pln

properties

purityNo data
delivery timeTo be confirmed by Chemat
Structural formula: {0} (CAS {1})

RK-24466 is a member of the class of pyrrolopyrimidines that is 7H-pyrrolo[2,3-d]pyrimidine substituted by amino, 4-phenoxyphenyl, and cyclopentyl groups at positions 4, 5 and 7, respectively. It is a potent inhibitor of Lck that inhibits Lck (64-509) and LckCD isoforms (IC50 of less than 1 and 2 nM, respectively). It has a role as a geroprotector and an EC 2.7.10.2 (non-specific protein-tyrosine kinase) inhibitor. It is a member of cyclopentanes, an aromatic amine, an aromatic ether, a pyrrolopyrimidine and a primary amino compound.

Source: ChEBI

Identity
Molecular formulaC23H22N4O
Molecular weight370.4 g/mol
IUPAC name7-cyclopentyl-5-(4-phenoxyphenyl)pyrrolo[2,3-d]pyrimidin-4-amine
InChIKeyFMETVQKSDIOGPX-UHFFFAOYSA-N
SMILESC1CCC(C1)N2C=C(C3=C(N=CN=C32)N)C4=CC=C(C=C4)OC5=CC=CC=C5

Computed by PubChem (NCBI)

Synonyms: 7-Cyclopentyl-5-(4-phenoxy)phenyl-7H-pyrrolo[2,3-d]pyrimidin-4-ylamine, 7-Cyclopentyl-5-(4-phenoxy)phenyl-7H-pyrrolo(2,3-d)pyrimidin-4-ylamine, 7-Cyclopentyl-5-(4-phenoxyphenyl)-7H-pyrrolo[2,3-d]pyrimidin-4-ylamine, 7-cyclopentyl-5-(4-phenoxyphenyl)pyrrolo[2,3-d]pyrimidin-4-amine, 4-Amino-5-(4-Phenoxyphenyl)-7h-Pyrrolo[2,3-D]pyrimidin-7-Yl-Cyclopentane, 3gen, 3vry, FMETVQKSDIOGPX-UHFFFAOYSA-N, Lopac-C-8863, Lopac0_000450
Isomers (same molecular formula)
4-[3-(4-piperazin-1-ylphenyl)-1H-indazol-6-yl]phenol C23H22N4O
N'-ethyl-4-(pyrido[3,4-b][1]benzazepin-11-ylmethyl)benzohydrazide C23H22N4O
N-(3-azidopropyl)-4-pyren-1-ylbutanamide C23H22N4O
N-(5-imidazo[1,2-a]pyrimidin-2-yl-2-methylphenyl)-2-phenylbutanamide C23H22N4O
7-[[3-[(pyridin-2-ylmethylamino)methyl]phenoxy]methyl]quinolin-2-amine C23H22N4O
2-N,4-N-dibenzyl-8-methoxyquinazoline-2,4-diamine C23H22N4O
(2R)-1-(1H-indol-3-yl)-3-[[5-[(E)-2-pyridin-4-ylethenyl]-3-pyridinyl]oxy]propan-2-amine C23H22N4O

Also listed as

Lck Inhibitor TRC CAS 213743-31-8
RK-24466/ 99.26% (existing batch purity) TargetMol CAS 213743-31-8
7-CYCLOPENTYL-5-(4-PHENOXY)PHENYL-7H-PYR Sigma-Aldrich CAS 213743-31-8
Lck Inhibitor 1PC X 1MG Sigma-Aldrich CAS 213743-31-8
RK-24466, 99.91% MedChemExpress CAS 213743-31-8
7-CYCLOPENTYL-5-(4-PHENOXYPHENYL)-7H-PYRROLO[2,3-D]PYRIMIDIN-4-YLAMINE, 98% Fluorochem CAS 213743-31-8
RK-24466, 99% Ambeed CAS 213743-31-8
7-Cyclopentyl-5-(4-phenoxyphenyl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine, 99% Chemat CAS 213743-31-8