Products 213743-31-8
CAS 213743-31-8 appears in our catalog under these names: Lck Inhibitor, RK-24466/ 99.26% (existing batch purity), RK–24466 (KIN 001–51), RK-24466 99%, 7-CYCLOPENTYL-5-(4-PHENOXY)PHENYL-7H-PYR. Offered by: TRC, TargetMol, GLPBio, Biosynth, Ambeed. Available pack sizes: 500mg, 1mg, 5mg, 10mg, 25mg, 50mg, 100mg, 10mM (in 1ml dmso).
RK-24466 is a member of the class of pyrrolopyrimidines that is 7H-pyrrolo[2,3-d]pyrimidine substituted by amino, 4-phenoxyphenyl, and cyclopentyl groups at positions 4, 5 and 7, respectively. It is a potent inhibitor of Lck that inhibits Lck (64-509) and LckCD isoforms (IC50 of less than 1 and 2 nM, respectively). It has a role as a geroprotector and an EC 2.7.10.2 (non-specific protein-tyrosine kinase) inhibitor. It is a member of cyclopentanes, an aromatic amine, an aromatic ether, a pyrrolopyrimidine and a primary amino compound.
Source: ChEBI
| Molecular formula | C23H22N4O |
|---|---|
| Molecular weight | 370.4 g/mol |
| IUPAC name | 7-cyclopentyl-5-(4-phenoxyphenyl)pyrrolo[2,3-d]pyrimidin-4-amine |
| InChIKey | FMETVQKSDIOGPX-UHFFFAOYSA-N |
| SMILES | C1CCC(C1)N2C=C(C3=C(N=CN=C32)N)C4=CC=C(C=C4)OC5=CC=CC=C5 |
Computed by PubChem (NCBI)
Synonyms:
7-Cyclopentyl-5-(4-phenoxy)phenyl-7H-pyrrolo[2,3-d]pyrimidin-4-ylamine, 7-Cyclopentyl-5-(4-phenoxy)phenyl-7H-pyrrolo(2,3-d)pyrimidin-4-ylamine, 7-Cyclopentyl-5-(4-phenoxyphenyl)-7H-pyrrolo[2,3-d]pyrimidin-4-ylamine, 7-cyclopentyl-5-(4-phenoxyphenyl)pyrrolo[2,3-d]pyrimidin-4-amine, 4-Amino-5-(4-Phenoxyphenyl)-7h-Pyrrolo[2,3-D]pyrimidin-7-Yl-Cyclopentane, 3gen, 3vry, FMETVQKSDIOGPX-UHFFFAOYSA-N, Lopac-C-8863, Lopac0_000450