Rigosertib, 95%
cas: 592542-59-1 — see every product listed under this CAS number, including other names
Rigosertib, 95% (CAS 592542-59-1) is a chemical reagent available from Chemat. Available pack sizes: 250mg, 100mg, 1g. Offered by: Combi-blocks.
| brand | Combi-blocks |
|---|---|
| catalog number | HG-3981-250mg |
| cas | 592542-59-1 |
| size | 250mg |
Documents:
Safety Data Sheet (MSDS)
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Available pack sizes
| brand | size | price | |
|---|---|---|---|
| Combi-blocks | 250mg | price on request | |
| Combi-blocks | 100mg | price on request | |
| Combi-blocks | 1g | price on request |
properties
| purity | 95% |
|---|---|
| delivery time | 1-2 weeks (only if in stock, to check click on availability) |
Rigosertib is an N-[2-methoxy-5-({[2-(2,4,6-trimethoxyphenyl)ethenyl]sulfonyl}methyl)phenyl]glycine in which the double bond has E-configuration. It is a non-ATP-competitive inhibitor of PLK1 with an IC50 of 9 nM and exhibits anti-cancer properties. It has a role as an EC 2.7.11.21 (polo kinase) inhibitor, an antineoplastic agent, a microtubule-destabilising agent and an apoptosis inducer. It is a conjugate acid of a rigosertib(1-).
Source: ChEBI
| Molecular formula | C21H25NO8S |
|---|---|
| Molecular weight | 451.5 g/mol |
| IUPAC name | 2-[2-methoxy-5-[[(E)-2-(2,4,6-trimethoxyphenyl)ethenyl]sulfonylmethyl]anilino]acetic acid |
| InChIKey | OWBFCJROIKNMGD-BQYQJAHWSA-N |
| SMILES | COC1=C(C=C(C=C1)CS(=O)(=O)/C=C/C2=C(C=C(C=C2OC)OC)OC)NCC(=O)O |
Computed by PubChem (NCBI)