Rigosertib, 99.01%
cas: 592542-59-1 — see every product listed under this CAS number, including other names
Rigosertib, 99.01% (CAS 592542-59-1) is a chemical reagent available from Chemat. Available pack sizes: 10 mg, 5 mg, 100 mg, 50 mg. Offered by: MedChemExpress.
| brand | MedChemExpress |
|---|---|
| catalog number | HY-12037A-10 mg |
| cas | 592542-59-1 |
| size | 10 mg |
| availability | Get quote |
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Available pack sizes
| brand | size | price | |
|---|---|---|---|
| MedChemExpress | 10 mg | 695.86 Pln | |
| MedChemExpress | 5 mg | 454.37 Pln | |
| MedChemExpress | 100 mg | 3719.10 Pln | |
| MedChemExpress | 50 mg | 2233.02 Pln |
properties
| delivery time | over 3 weeks |
|---|---|
| purity | 99.01% |
Rigosertib is an N-[2-methoxy-5-({[2-(2,4,6-trimethoxyphenyl)ethenyl]sulfonyl}methyl)phenyl]glycine in which the double bond has E-configuration. It is a non-ATP-competitive inhibitor of PLK1 with an IC50 of 9 nM and exhibits anti-cancer properties. It has a role as an EC 2.7.11.21 (polo kinase) inhibitor, an antineoplastic agent, a microtubule-destabilising agent and an apoptosis inducer. It is a conjugate acid of a rigosertib(1-).
Source: ChEBI
| Molecular formula | C21H25NO8S |
|---|---|
| Molecular weight | 451.5 g/mol |
| IUPAC name | 2-[2-methoxy-5-[[(E)-2-(2,4,6-trimethoxyphenyl)ethenyl]sulfonylmethyl]anilino]acetic acid |
| InChIKey | OWBFCJROIKNMGD-BQYQJAHWSA-N |
| SMILES | COC1=C(C=C(C=C1)CS(=O)(=O)/C=C/C2=C(C=C(C=C2OC)OC)OC)NCC(=O)O |
Computed by PubChem (NCBI)