Rigosertib
cas: 592542-59-1 — see every product listed under this CAS number, including other names
Rigosertib (CAS 592542-59-1) is a chemical reagent available from Chemat. Available pack sizes: 500mg, 10mg, 100mg, 5mg, 10mM (in 1ml dmso), 50mg. Offered by: TRC, GLPBio.
| brand | TRC |
|---|---|
| catalog number | TRC-R590713-500MG |
| cas | 592542-59-1 |
| size | 500mg |
Need more information?
Ask us about this product — we're happy to help.
Available pack sizes
| brand | size | price | |
|---|---|---|---|
| TRC | 500mg | price on request | |
| GLPBio | 10mg | 1065.09 Pln | |
| GLPBio | 100mg | 4580.15 Pln | |
| GLPBio | 5mg | 802.98 Pln | |
| GLPBio | 10mM (in 1ml dmso) | 845.11 Pln | |
| GLPBio | 50mg | 3016.86 Pln |
properties
| purity | No data |
|---|---|
| delivery time | To be confirmed by Chemat |
Rigosertib is an N-[2-methoxy-5-({[2-(2,4,6-trimethoxyphenyl)ethenyl]sulfonyl}methyl)phenyl]glycine in which the double bond has E-configuration. It is a non-ATP-competitive inhibitor of PLK1 with an IC50 of 9 nM and exhibits anti-cancer properties. It has a role as an EC 2.7.11.21 (polo kinase) inhibitor, an antineoplastic agent, a microtubule-destabilising agent and an apoptosis inducer. It is a conjugate acid of a rigosertib(1-).
Source: ChEBI
| Molecular formula | C21H25NO8S |
|---|---|
| Molecular weight | 451.5 g/mol |
| IUPAC name | 2-[2-methoxy-5-[[(E)-2-(2,4,6-trimethoxyphenyl)ethenyl]sulfonylmethyl]anilino]acetic acid |
| InChIKey | OWBFCJROIKNMGD-BQYQJAHWSA-N |
| SMILES | COC1=C(C=C(C=C1)CS(=O)(=O)/C=C/C2=C(C=C(C=C2OC)OC)OC)NCC(=O)O |
Computed by PubChem (NCBI)