Simurosertib, 99%, 99%
cas: 1330782-76-7 — see every product listed under this CAS number, including other names
Simurosertib, 99%, 99% (CAS 1330782-76-7) is a chemical reagent available from Chemat. Available pack sizes: 2mg, 10mg, 25mg, 50mg, 100mg, 250mg, 1g, 5mg. Offered by: Chemat.
| brand | Chemat |
|---|---|
| catalog number | Ch12FN9X-2mg |
| cas | 1330782-76-7 |
| size | 2mg |
| availability | 5g |
Need more information?
Ask us about this product — we're happy to help.
Available pack sizes
| brand | size | price | |
|---|---|---|---|
| Chemat | 2mg | 280.40 Pln | |
| Chemat | 10mg | 674.00 Pln | |
| Chemat | 25mg | 1106.00 Pln | |
| Chemat | 50mg | 1730.00 Pln | |
| Chemat | 100mg | 2733.20 Pln | |
| Chemat | 250mg | 4605.20 Pln | |
| Chemat | 1g | 14598.80 Pln | |
| Chemat | 5mg | 434.00 Pln |
properties
| purity | 99% |
|---|---|
| delivery time | 3 weeks |
Simurosertib is an orally bioavailable inhibitor of cell division cycle 7 (cell division cycle 7-related protein kinase; CDC7), with potential antineoplastic activity. Upon administration, simurosertib binds to and inhibits CDC7; this prevents the initiation of DNA replication during mitosis, which causes cell cycle arrest and induces apoptosis. This inhibits cell growth in CDC7-overexpressing tumor cells.
Source: ChEBI
| Molecular formula | C17H19N5OS |
|---|---|
| Molecular weight | 341.4 g/mol |
| IUPAC name | 2-[(2S)-1-azabicyclo[2.2.2]octan-2-yl]-6-(5-methyl-1H-pyrazol-4-yl)-3H-thieno[3,2-d]pyrimidin-4-one |
| InChIKey | XGVXKJKTISMIOW-ZDUSSCGKSA-N |
| SMILES | CC1=C(C=NN1)C2=CC3=C(S2)C(=O)NC(=N3)[C@@H]4CC5CCN4CC5 |
Computed by PubChem (NCBI)