TIBOLONE, BRITISH PHARMACOPOEIA (BP) REF

cas: 5630-53-5 — see every product listed under this CAS number, including other names

TIBOLONE, BRITISH PHARMACOPOEIA (BP) REF (CAS 5630-53-5) is a chemical reagent available from Chemat. Available pack sizes: 1EA. Offered by: Sigma-Aldrich.

brandSigma-Aldrich
catalog numberBP848
cas5630-53-5
size1EA
availability availability
Documents: Safety Data Sheet (MSDS)
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Available pack sizes

brand size price
Sigma-Aldrich 1EA 1230.00 Pln

properties

purityNo data
delivery time1-2 weeks (only if in stock, to check click on availability)
Structural formula: {0} (CAS {1})

Tibolone is estran-3-one with a double bond between positions 5 and 10, and bearing both an ethynyl group and a hydroxy group at position 17 (R-configuration). A synthetic steroid hormone drug which acts as an agonist at all five type I steroid hormone receptors, it is used in the prevention of postmenopausal osteoporosis and for treatment of endometriosis. It has a role as a bone density conservation agent and a hormone agonist. It is a 17beta-hydroxy steroid and a terminal acetylenic compound.

Source: ChEBI

Identity
Molecular formulaC21H28O2
Molecular weight312.4 g/mol
IUPAC name(7R,8R,9S,13S,14S,17R)-17-ethynyl-17-hydroxy-7,13-dimethyl-1,2,4,6,7,8,9,11,12,14,15,16-dodecahydrocyclopenta[a]phenanthren-3-one
InChIKeyWZDGZWOAQTVYBX-XOINTXKNSA-N
SMILESC[C@@H]1CC2=C(CCC(=O)C2)[C@@H]3[C@@H]1[C@@H]4CC[C@]([C@]4(CC3)C)(C#C)O

Computed by PubChem (NCBI)

Synonyms: tibolone, Liviella, Livial, Org OD 14, Tibolona, Xyvion, Tibolonum, 17-Hydroxy-7alpha-methyl-19-nor-17alpha-pregn-5(10)-en-20-yn-3-one, 17alpha-ethynyl-17beta-hydroxy-7alpha-methylestr-5(10)-en-3-one, tibilone
Related forms of this compound
(7S,8R,9S,13S,14S,17R)-17-ethynyl-17-hydroxy-7,13-dimethyl-1,2,4,6,7,8,9,11,12,14,15,16-dodecahydrocyclopenta[a]phenanthren-3-one C21H28O2
Isomers (same molecular formula)
(8S,9R,10S,13R,14R,17S)-13-ethyl-17-ethynyl-17-hydroxy-1,2,6,7,8,9,10,11,12,14,15,16-dodecahydrocyclopenta[a]phenanthren-3-one C21H28O2
(8R,9S,10R,13S,14S,17Z)-17-ethylidene-10,13-dimethyl-1,2,6,7,8,9,11,12,14,15-decahydrocyclopenta[a]phenanthrene-3,16-dione C21H28O2
2,6-ditert-butyl-4-phenylmethoxyphenol C21H28O2
(8R,9S,10R,13S,14S,17E)-17-ethylidene-10,13-dimethyl-1,2,6,7,8,9,11,12,14,15-decahydrocyclopenta[a]phenanthrene-3,16-dione C21H28O2
(8R,9S,10R,13S,14S,17R)-13-ethyl-17-ethynyl-17-hydroxy-1,2,6,7,8,9,10,11,12,14,15,16-dodecahydrocyclopenta[a]phenanthren-3-one C21H28O2
(8S,10S,13S,14S,17S)-17-acetyl-10,13-dimethyl-1,2,6,7,8,12,14,15,16,17-decahydrocyclopenta[a]phenanthren-3-one C21H28O2
(8S,9S,10R,13S,14S,17S)-17-acetyl-10,13-dimethyl-1,2,6,7,8,9,14,15,16,17-decahydrocyclopenta[a]phenanthren-3-one C21H28O2
(8R,9S,10R,13S,14S,17S)-13-ethyl-17-ethynyl-17-hydroxy-1,2,6,7,8,9,10,11,12,14,15,16-dodecahydrocyclopenta[a]phenanthren-3-one C21H28O2
(8S,9S,13S,14S,17R)-13-ethyl-17-ethynyl-17-hydroxy-1,2,4,6,7,8,9,11,12,14,15,16-dodecahydrocyclopenta[a]phenanthren-3-one C21H28O2
(8R,9S,10R,13R,17S)-17-acetyl-10,13-dimethyl-1,2,6,7,8,9,11,12,16,17-decahydrocyclopenta[a]phenanthren-3-one C21H28O2
(8R,9S,13S,14S)-13-methyl-3-propoxy-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthren-17-one C21H28O2

Also listed as

Tibolone (1mg/ml in Acetonitrile) TRC CAS 5630-53-5
Tibolone, >95% (HPLC) TRC CAS 5630-53-5
Tibolone Mikromol CAS 5630-53-5
Tibolone, 99.9% MedChemExpress CAS 5630-53-5
Tibolone (Standard) MedChemExpress CAS 5630-53-5