Products 5630-53-5

CAS 5630-53-5 appears in our catalog under these names: Tibolone (1mg/ml in Acetonitrile), Tibolone, >95% (HPLC), Tibolone, TIBOLONE, BRITISH PHARMACOPOEIA (BP) REF, Tibolone, 99.9%. Offered by: TRC, Mikromol, LoGiCal, TargetMol, GLPBio. Available pack sizes: 10x1ml, 100mg, 1g, 50mg, 250mg, 10mg, 25mg, 500mg.

Tibolone (1mg/ml in Acetonitrile)
TRC
  • size: 10x1ml
  • Variants: 1
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Tibolone, >95% (HPLC)
TRC
  • size: 100mg, 1g, 50mg
  • Variants: 3
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Tibolone
Mikromol, LoGiCal, TargetMol
  • size: 250mg, 10mg, 25mg, 50mg
  • Variants: 13
from 452.11
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TIBOLONE, BRITISH PHARMACOPOEIA (BP) REF
Sigma-Aldrich
  • size: 1EA
  • Variants: 1
from 1230.00
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Tibolone, 99.9%
MedChemExpress
  • size: 25 mg, 10mM/1mL, 100 mg, 50 mg
  • Variants: 4
from 361.49
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Tibolone (Standard)
MedChemExpress
  • size: 25 mg, 10 mg, 100 mg, 5 mg
  • Variants: 5
from 310.40
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Structural formula: {0} (CAS {1})

Tibolone is estran-3-one with a double bond between positions 5 and 10, and bearing both an ethynyl group and a hydroxy group at position 17 (R-configuration). A synthetic steroid hormone drug which acts as an agonist at all five type I steroid hormone receptors, it is used in the prevention of postmenopausal osteoporosis and for treatment of endometriosis. It has a role as a bone density conservation agent and a hormone agonist. It is a 17beta-hydroxy steroid and a terminal acetylenic compound.

Source: ChEBI

Identity
Molecular formulaC21H28O2
Molecular weight312.4 g/mol
IUPAC name(7R,8R,9S,13S,14S,17R)-17-ethynyl-17-hydroxy-7,13-dimethyl-1,2,4,6,7,8,9,11,12,14,15,16-dodecahydrocyclopenta[a]phenanthren-3-one
InChIKeyWZDGZWOAQTVYBX-XOINTXKNSA-N
SMILESC[C@@H]1CC2=C(CCC(=O)C2)[C@@H]3[C@@H]1[C@@H]4CC[C@]([C@]4(CC3)C)(C#C)O

Computed by PubChem (NCBI)

Synonyms: tibolone, Liviella, Livial, Org OD 14, Tibolona, Xyvion, Tibolonum, 17-Hydroxy-7alpha-methyl-19-nor-17alpha-pregn-5(10)-en-20-yn-3-one, 17alpha-ethynyl-17beta-hydroxy-7alpha-methylestr-5(10)-en-3-one, tibilone
Related forms of this compound
(7S,8R,9S,13S,14S,17R)-17-ethynyl-17-hydroxy-7,13-dimethyl-1,2,4,6,7,8,9,11,12,14,15,16-dodecahydrocyclopenta[a]phenanthren-3-one C21H28O2
Isomers (same molecular formula)
(8S,9R,10S,13R,14R,17S)-13-ethyl-17-ethynyl-17-hydroxy-1,2,6,7,8,9,10,11,12,14,15,16-dodecahydrocyclopenta[a]phenanthren-3-one C21H28O2
(8R,9S,10R,13S,14S,17Z)-17-ethylidene-10,13-dimethyl-1,2,6,7,8,9,11,12,14,15-decahydrocyclopenta[a]phenanthrene-3,16-dione C21H28O2
2,6-ditert-butyl-4-phenylmethoxyphenol C21H28O2
(8R,9S,10R,13S,14S,17E)-17-ethylidene-10,13-dimethyl-1,2,6,7,8,9,11,12,14,15-decahydrocyclopenta[a]phenanthrene-3,16-dione C21H28O2
(8R,9S,10R,13S,14S,17R)-13-ethyl-17-ethynyl-17-hydroxy-1,2,6,7,8,9,10,11,12,14,15,16-dodecahydrocyclopenta[a]phenanthren-3-one C21H28O2
(8S,10S,13S,14S,17S)-17-acetyl-10,13-dimethyl-1,2,6,7,8,12,14,15,16,17-decahydrocyclopenta[a]phenanthren-3-one C21H28O2
(8S,9S,10R,13S,14S,17S)-17-acetyl-10,13-dimethyl-1,2,6,7,8,9,14,15,16,17-decahydrocyclopenta[a]phenanthren-3-one C21H28O2
(8R,9S,10R,13S,14S,17S)-13-ethyl-17-ethynyl-17-hydroxy-1,2,6,7,8,9,10,11,12,14,15,16-dodecahydrocyclopenta[a]phenanthren-3-one C21H28O2
(8S,9S,13S,14S,17R)-13-ethyl-17-ethynyl-17-hydroxy-1,2,4,6,7,8,9,11,12,14,15,16-dodecahydrocyclopenta[a]phenanthren-3-one C21H28O2
(8R,9S,10R,13R,17S)-17-acetyl-10,13-dimethyl-1,2,6,7,8,9,11,12,16,17-decahydrocyclopenta[a]phenanthren-3-one C21H28O2
(8R,9S,13S,14S)-13-methyl-3-propoxy-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthren-17-one C21H28O2