Thiolutin (Standard)
cas: 87-11-6 — see every product listed under this CAS number, including other names
Thiolutin (Standard) (CAS 87-11-6) is a chemical reagent available from Chemat. Available pack sizes: Get quote. Offered by: MedChemExpress.
| brand | MedChemExpress |
|---|---|
| catalog number | HY-N6712R-Get quote |
| cas | 87-11-6 |
| size | Get quote |
| availability | Get quote |
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Available pack sizes
| brand | size | price | |
|---|---|---|---|
| MedChemExpress | Get quote | price on request |
properties
| delivery time | to confirm by Chemat |
|---|---|
| purity | no data |
Thiolutin is a dithiolopyrrolone antibiotic that is 4,5-dihydro[1,2]dithiolo[4,3-b]pyrrole in which the hydrogens at positions 4,5 and 6 have been replaced by methyl, oxo and acetamido groups, respectively. It is a potent inhibitor of RNA polymerases, inhibits the angiogenesis of human umbilical vein endothelial cells, and also inhibits JAMM metalloproteases. It has a role as a toxin, an antibacterial agent, an antineoplastic agent, an antifungal agent, an EC 2.7.7.6 (RNA polymerase) inhibitor, a chelator, a protein synthesis inhibitor, an angiogenesis inhibitor, a marine metabolite and a bacterial metabolite. It is a dithiolopyrrolone antibiotic and a member of acetamides. It is functionally related to a holomycin.
Source: ChEBI
| Molecular formula | C8H8N2O2S2 |
|---|---|
| Molecular weight | 228.3 g/mol |
| IUPAC name | N-(4-methyl-5-oxodithiolo[4,3-b]pyrrol-6-yl)acetamide |
| InChIKey | MHMRAFONCSQAIA-UHFFFAOYSA-N |
| SMILES | CC(=O)NC1=C2C(=CSS2)N(C1=O)C |
Computed by PubChem (NCBI)
Synonyms:
Thiolutin, Acetopyrrothin, Acetopyrrothine, N-(4,5-dihydro-4-methyl-5-oxo-1,2-dithiolo[4,3-b]pyrrol-6-yl)acetamide, 3-Acetamido-5-methylpyrrolin-4-one(4,3-d)-1,2-dithiole, N-(4,5-Dihydro-4-methyl-5-oxo-1,2-dithiolo(4,3-b)pyrrol-6-yl)acetamide, N-(4-methyl-5-oxodithiolo[4,3-b]pyrrol-6-yl)acetamide, 6-Acetamido-4-methyl-1,2-dithiolo(4,3-b)pyrrol-5(4H)-one, N-{4-methyl-5-oxo-4H,5H-[1,2]dithiolo[4,3-b]pyrrol-6-yl}acetamide, N-(4-methyl-5-oxo-4,5-dihydro[1,2]dithiolo[4,3-b]pyrrol-6-yl)acetamide