CAS 100643-71-8 appears in our catalog under these names: Loratadine EP Impurity D (Loratadine USP Related Compound A, Rupatadine EP Impurity B, Desloratadine), Loratadine Impurity D (Desloratadine)（EP ）, Desloratadine, >95% (HPLC), Desloratadine, 8-Chloro-11-(piperidin-4-ylidene)-6,11-dihydro-5H-benzo(5,6)cyclohepta(1,2-b)pyridine (Descarboethoxyloratadine, Desloratadine). Offered by: Chemat Brand, TRC, Dr. Ehrenstorfer, Mikromol, TargetMol. Available pack sizes: on request, 100mg, 10mg, 50mg, 25mg, 250mg, 1g, 200mg.
Desloratadine is loratadine in which the ethoxycarbonyl group attached to the piperidine ring is replaced by hydrogen. The major metabolite of loratidine, desloratadine is an antihistamine which is used for the symptomatic relief of allergic conditions including rhinitis and chronic urticaria. It does not readily enter the central nervous system, so does not cause drowsiness. It has a role as a H1-receptor antagonist, a cholinergic antagonist, a drug metabolite and an anti-allergic agent.
Source: ChEBI
| Molecular formula | C19H19ClN2 |
|---|---|
| Molecular weight | 310.8 g/mol |
| IUPAC name | 13-chloro-2-piperidin-4-ylidene-4-azatricyclo[9.4.0.03,8]pentadeca-1(11),3(8),4,6,12,14-hexaene |
| InChIKey | JAUOIFJMECXRGI-UHFFFAOYSA-N |
| SMILES | C1CC2=C(C=CC(=C2)Cl)C(=C3CCNCC3)C4=C1C=CC=N4 |
Computed by PubChem (NCBI)