Products 101714-41-4
CAS 101714-41-4 appears in our catalog under these names: BIX, >95% (HPLC), BiP inducer X, BIX, BiP inducer X 95%, 2-(Cyanosulfanyl)-1-(3,4-Dihydroxyphenyl)Ethan-1-One, 98%, 98%. Offered by: TRC, TargetMol, GLPBio, Biosynth, Ambeed. Available pack sizes: 100mg, 25mg, 5mg, 10mg, 50mg, 200mg, 1g, 250mg.
2-(3,4-dihydroxyphenyl)-2-oxoethyl thiocyanate is a member of the class of thiocyanates that is 3,4-dihydroxyacetophenone in which one of the methyl hydrogens has been replaced by the sulfur of a cyanosulfanediyl (-SCN) group. It has been found to induce the expression of the endoplasmic reticulum chaperone protein GRP78 (78 kDa glucose-regulated protein, BiP, a highly conserved member of the 70 kDa heat shock protein family) leading to an attenuation of the unfolded protein response. It protects neuronal cells and retinal cells from endoplasmic reticulum (ER)-stress induced cell death. It is a member of thiocyanates, a member of catechols and an aromatic ketone.
Source: ChEBI
| Molecular formula | C9H7NO3S |
|---|---|
| Molecular weight | 209.22 g/mol |
| IUPAC name | [2-(3,4-dihydroxyphenyl)-2-oxoethyl] thiocyanate |
| InChIKey | SVFLBLCWKKQKDW-UHFFFAOYSA-N |
| SMILES | C1=CC(=C(C=C1C(=O)CSC#N)O)O |
Computed by PubChem (NCBI)
Synonyms:
2-(Cyanosulfanyl)-1-(3,4-dihydroxyphenyl)ethan-1-one, BiP inducer X, 2-(3,4-dihydroxyphenyl)-2-oxoethyl thiocyanate, BIX, Thiocyanic acid, 2-(3,4-dihydroxyphenyl)-2-oxoethyl ester, 1-(3,4-dihydroxyphenyl)-2-thiocyanate-ethanone, [2-(3,4-dihydroxyphenyl)-2-oxoethyl] thiocyanate, BiP Inducer X (BIX), [2-(3,4-dihydroxyphe, orb1304590