Products 107868-30-4
CAS 107868-30-4 appears in our catalog under these names: Exemestane, Exemestane, 98.00%, Exemestane, 99.97%, Exemestane (Standard), 99.63%. Offered by: Chemat Brand, TRC, Mikromol, LoGiCal, Dr. Ehrenstorfer. Available pack sizes: on request, 10mg, 25mg, 5mg, 250mg, 100mg, 10mM (in 1ml dmso), 50mg.
Exemestane is a 17-oxo steroid that is androsta-1,4-diene-3,17-dione in which the hydrogens at position 6 are replaced by a double bond to a methylene group. A selective inhibitor of the aromatase (oestrogen synthase) system, it is used in the treatment of advanced breast cancer. It has a role as an antineoplastic agent, a xenobiotic, an EC 1.14.14.14 (aromatase) inhibitor and an environmental contaminant. It is a 17-oxo steroid and a 3-oxo-Delta(1),Delta(4)-steroid. It derives from a hydride of an androstane.
Source: ChEBI
| Molecular formula | C20H24O2 |
|---|---|
| Molecular weight | 296.4 g/mol |
| IUPAC name | (8R,9S,10R,13S,14S)-10,13-dimethyl-6-methylidene-7,8,9,11,12,14,15,16-octahydrocyclopenta[a]phenanthrene-3,17-dione |
| InChIKey | BFYIZQONLCFLEV-DAELLWKTSA-N |
| SMILES | C[C@]12CC[C@H]3[C@H]([C@@H]1CCC2=O)CC(=C)C4=CC(=O)C=C[C@]34C |
Computed by PubChem (NCBI)