CAS 1112978-84-3 appears in our catalog under these names: Leucettine L41, 97%, Leucettine L41, Leucettine L41, Leucettine L41, 98.00%, Leucettine L41 99%. Offered by: AmBeed, TargetMol, GLPBio, Chemat, Biosynth. Available pack sizes: 5mg, 1mg, 10mg, 25mg, 2mg, 50mg, 100mg, 250mg.
Leucettine L41 is a member of the class of benzodioxoles that is 1,3-benzodioxole substituted by a (2-anilino-5-oxo-1,5-dihydro-4H-imidazol-4-ylidene)methyl group at position 5. It is an inhibitor of DYRK1A, DYRK2, CLK1, and CLK3 (IC50s = 0.04, 0.035, 0.015, and 4.5 M, respectively). It has a role as an autophagy inducer, an EC 2.7.12.1 (dual-specificity kinase) inhibitor, a neuroprotective agent, a nootropic agent and an EC 2.7.11.22 (cyclin-dependent kinase) inhibitor. It is an imidazolone, a member of benzodioxoles and a substituted aniline.
Source: ChEBI
| Molecular formula | C17H13N3O3 |
|---|---|
| Molecular weight | 307.30 g/mol |
| IUPAC name | (4Z)-2-anilino-4-(1,3-benzodioxol-5-ylmethylidene)-1H-imidazol-5-one |
| InChIKey | PGPHHJBZEGSUNE-JYRVWZFOSA-N |
| SMILES | C1OC2=C(O1)C=C(C=C2)/C=C\3/C(=O)NC(=N3)NC4=CC=CC=C4 |
Computed by PubChem (NCBI)