CAS 120279-96-1 appears in our catalog under these names: (4S,6S)-4-(Ethylamino)-6-methyl-5,6-dihydro-4H-thieno[2,3-b]thiopyran-2-sulfonamide 7,7-dioxide, 98+%, Dorzolamide. Offered by: Chemat Brand, GLPBio, MedChemExpress. Available pack sizes: on request, 10mg, 100mg, 25mg, 50mg, Get quote.
Dorzolamide is 5,6-Dihydro-4H-thieno[2,3-b]thiopyran-2-sulfonamide 7,7-dioxide in which hydrogens at the 4 and 6 positions are substituted by ethylamino and methyl groups, respectively (4S, trans-configuration). A carbonic anhydrase inhibitor, it is used as the hydrochloride in ophthalmic solutions to lower increased intraocular pressure in the treatment of open-angle glaucoma and ocular hypertension. It has a role as an EC 4.2.1.1 (carbonic anhydrase) inhibitor, an antihypertensive agent and an antiglaucoma drug. It is a member of thiophenes and a sulfonamide.
Source: ChEBI
| Molecular formula | C10H16N2O4S3 |
|---|---|
| Molecular weight | 324.4 g/mol |
| IUPAC name | (4S,6S)-4-(ethylamino)-6-methyl-7,7-dioxo-5,6-dihydro-4H-thieno[2,3-b]thiopyran-2-sulfonamide |
| InChIKey | IAVUPMFITXYVAF-XPUUQOCRSA-N |
| SMILES | CCN[C@H]1C[C@@H](S(=O)(=O)C2=C1C=C(S2)S(=O)(=O)N)C |
Computed by PubChem (NCBI)