Products 139066-77-6

CAS 139066-77-6 is the registry number for (4S, 6R)-Dorzolamide EP Impurity B. Offered by: Chemat Brand. Available pack sizes: on request.

(4S, 6R)-Dorzolamide EP Impurity B
Chemat Brand
  • size: on request
  • Variants: 1
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Structural formula: {0} (CAS {1})

Dorzolamide is 5,6-Dihydro-4H-thieno[2,3-b]thiopyran-2-sulfonamide 7,7-dioxide in which hydrogens at the 4 and 6 positions are substituted by ethylamino and methyl groups, respectively (4S, trans-configuration). A carbonic anhydrase inhibitor, it is used as the hydrochloride in ophthalmic solutions to lower increased intraocular pressure in the treatment of open-angle glaucoma and ocular hypertension. It has a role as an EC 4.2.1.1 (carbonic anhydrase) inhibitor, an antihypertensive agent and an antiglaucoma drug. It is a member of thiophenes and a sulfonamide.

Source: ChEBI

Identity
Molecular formulaC10H16N2O4S3
Molecular weight324.4 g/mol
IUPAC name(4S,6S)-4-(ethylamino)-6-methyl-7,7-dioxo-5,6-dihydro-4H-thieno[2,3-b]thiopyran-2-sulfonamide
InChIKeyIAVUPMFITXYVAF-XPUUQOCRSA-N
SMILESCCN[C@H]1C[C@@H](S(=O)(=O)C2=C1C=C(S2)S(=O)(=O)N)C

Computed by PubChem (NCBI)

Synonyms: dorzolamide, 4S,6S-Dorzolamide, Dorzolamida, Dorzolamide, trans-(-)-, Dorzolamidum, Dorzant, Dorzolamide (INN), Trusopt (TN), DORZOLAMIDE [INN], Dorzolamide (DZA)
Related forms of this compound
(4S,6S)-4-(ethylamino)-6-methyl-7,7-dioxo-5,6-dihydro-4H-thieno[2,3-b]thiopyran-2-sulfonamide C10H16N2O4S3
(4R,6R)-4-(ethylamino)-6-methyl-7,7-dioxo-5,6-dihydro-4H-thieno[2,3-b]thiopyran-2-sulfonamide C10H16N2O4S3
(4R,6S)-4-(ethylamino)-6-methyl-7,7-dioxo-5,6-dihydro-4H-thieno[2,3-b]thiopyran-2-sulfonamide C10H16N2O4S3
(4R,6R)-4-(ethylamino)-6-methyl-7,7-dioxo-5,6-dihydro-4H-thieno[2,3-b]thiopyran-2-sulfonamide C10H16N2O4S3
(4R,6S)-4-(ethylamino)-6-methyl-7,7-dioxo-5,6-dihydro-4H-thieno[2,3-b]thiopyran-2-sulfonamide C10H16N2O4S3
Isomers (same molecular formula)
(4S,6S)-4-(ethylamino)-6-methyl-7,7-dioxo-5,6-dihydro-4H-thieno[2,3-b]thiopyran-3-sulfonamide C10H16N2O4S3