CAS 149647-78-9 appears in our catalog under these names: Vorinostat, 98%, Vorinostat, Suberoylanilide Hydroxamic Acid, >95% (HPLC), Vorinostat (SAHA, MK0683), Suberoylanilide hydroxamic acid, 98% . Offered by: Combi-blocks, Chemat Brand, Mikromol, TRC, GLPBio. Available pack sizes: 25g, 5g, 1g, on request, 250mg, 100mg, 500mg, 10mM (in 1ml dmso).
Vorinostat is a dicarboxylic acid diamide comprising suberic (octanedioic) acid coupled to aniline and hydroxylamine. A histone deacetylase inhibitor, it is marketed under the name Zolinza for the treatment of cutaneous T cell lymphoma (CTCL). It has a role as an antineoplastic agent, an EC 3.5.1.98 (histone deacetylase) inhibitor and an apoptosis inducer. It is a hydroxamic acid and a dicarboxylic acid diamide. It is functionally related to a hydroxylamine, an aniline and a suberic acid.
Source: ChEBI
| Molecular formula | C14H20N2O3 |
|---|---|
| Molecular weight | 264.32 g/mol |
| IUPAC name | N'-hydroxy-N-phenyloctanediamide |
| InChIKey | WAEXFXRVDQXREF-UHFFFAOYSA-N |
| SMILES | C1=CC=C(C=C1)NC(=O)CCCCCCC(=O)NO |
Computed by PubChem (NCBI)