Products 209216-23-9
CAS 209216-23-9 appears in our catalog under these names: Entecavir Monohydrate, >95% (HPLC), Entecavir Monohydrate, Entecavir Hydrate, Entecavir hydrate, 99.00%, Entecavir hydrate. Offered by: TRC, Mikromol, LoGiCal, GLPBio, Chemat. Available pack sizes: 10mg, 1mg, 2mg, 250mg, 100mg, 25mg, 5mg, 1000mg.
Entecavir hydrate is the monohydrate form of entecavir. A synthetic analogue of 2'-deoxyguanosine, entecavir is a nucleoside reverse transcriptase inhibitor with selective antiviral activity against hepatitis B virus. It is phosphorylated intracellularly to the active triphosphate form, which competes with deoxyguanosine triphosphate, the natural substrate of hepatitis B virus reverse transcriptase, inhibiting every stage of the enzyme's activity, although it has no activity against HIV. Enteclavir is used for the treatment of chronic hepatitis B. It has a role as an antiviral drug and an EC 2.7.7.49 (RNA-directed DNA polymerase) inhibitor. It contains an entecavir (anhydrous).
Source: ChEBI
| Molecular formula | C12H17N5O4 |
|---|---|
| Molecular weight | 295.29 g/mol |
| IUPAC name | 2-amino-9-[(1S,3R,4S)-4-hydroxy-3-(hydroxymethyl)-2-methylidenecyclopentyl]-1H-purin-6-one;hydrate |
| InChIKey | YXPVEXCTPGULBZ-WQYNNSOESA-N |
| SMILES | C=C1[C@H](C[C@@H]([C@H]1CO)O)N2C=NC3=C2N=C(NC3=O)N.O |
Computed by PubChem (NCBI)