Products 2411890-36-1
CAS 2411890-36-1 appears in our catalog under these names: PARP11 inhibitor ITK7, PARP11 inhibitor ITK7, 99.77%, 99.77%, PARP11 inhibitor ITK7, 99.70%. Offered by: GLPBio, Chemat, MedChemExpress. Available pack sizes: 10mg, 25mg, 1mg, 5mg, 5 mg, 100 mg, 25 mg, 10 mg.
ITK7 is a member of the class of quinazolines that is quinazolin-4(3H)-one substituted by (pyrimidin-2-ylsulfanyl)methyl, prop-1-yn-1-yl, and methyl groups at positions 2, 7, and 8, respectively. It is a potent PARP11 inhibitor (IC50 = 14 nM). It has a role as an EC 2.4.2.30 (NAD(+) ADP-ribosyltransferase) inhibitor. It is an organic sulfide, a member of quinazolines, a member of pyrimidines and an arylacetylene.
Source: ChEBI
| Molecular formula | C17H14N4OS |
|---|---|
| Molecular weight | 322.4 g/mol |
| IUPAC name | 8-methyl-7-prop-1-ynyl-2-(pyrimidin-2-ylsulfanylmethyl)-3H-quinazolin-4-one |
| InChIKey | VRECINGNBPANGK-UHFFFAOYSA-N |
| SMILES | CC#CC1=C(C2=C(C=C1)C(=O)NC(=N2)CSC3=NC=CC=N3)C |
Computed by PubChem (NCBI)