Products 465-65-6
CAS 465-65-6 appears in our catalog under these names: Naloxone, >95% (HPLC), Naloxone, Naloxone, 99.71%, Naloxone (Standard). Offered by: TRC, Biosynth, MedChemExpress. Available pack sizes: 100mg, 10mg, 1mg, 5mg, 25mg, 25 mg, 50 mg, 10 mg.
Naloxone is a synthetic morphinane alkaloid that is morphinone in which the enone double bond has been reduced to a single bond, the hydrogen at position 14 has been replaced by a hydroxy group, and the methyl group attached to the nitrogen has been replaced by an allyl group. A specific opioid antagonist, it is used (commonly as its hydrochloride salt) to reverse the effects of opioids, both following their use of opioids during surgery and in cases of known or suspected opioid overdose. It has a role as a central nervous system depressant, a mu-opioid receptor antagonist and an antidote to opioid poisoning. It is a morphinane alkaloid, a tertiary alcohol and an organic heteropentacyclic compound. It is a conjugate base of a naloxone(1+). It derives from a hydride of a morphinan.
Source: ChEBI
| Molecular formula | C19H21NO4 |
|---|---|
| Molecular weight | 327.4 g/mol |
| IUPAC name | (4R,4aS,7aR,12bS)-4a,9-dihydroxy-3-prop-2-enyl-2,4,5,6,7a,13-hexahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinolin-7-one |
| InChIKey | UZHSEJADLWPNLE-GRGSLBFTSA-N |
| SMILES | C=CCN1CC[C@]23[C@@H]4C(=O)CC[C@]2([C@H]1CC5=C3C(=C(C=C5)O)O4)O |
Computed by PubChem (NCBI)