Products 78613-35-1
CAS 78613-35-1 appears in our catalog under these names: Amorolfine Impurity 20, Amorolfine, >95% (HPLC), Amorolfine. Offered by: Chemat Brand, TRC, MedChemExpress. Available pack sizes: on request, 20mg, 40mg, Get quote.
Amorolfine is a member of the class of morpholines that is cis-2,6-dimethylmorpholine in which the hydrogen attached to the nitrogen is replaced by a racemic 2-methyl-3-[p-(2-methylbutan-2-yl)phenyl]propyl group. An inhibitor of the action of squalene monooxygenase, 14 reductase and D7-D8 isomerase and an antifungal agent, it is used (generally as its hydrochloride salt) for the topical treatment of fungal nail and skin infections. It has a role as an EC 1.14.13.132 (squalene monooxygenase) inhibitor, an EC 1.3.1.70 (Delta(14)-sterol reductase) inhibitor and an EC 5.3.3.5 (cholestenol Delta-isomerase) inhibitor. It is a tertiary amino compound and a morpholine antifungal drug. It is a conjugate base of an amorolfine(1+).
Source: ChEBI
| Molecular formula | C21H35NO |
|---|---|
| Molecular weight | 317.5 g/mol |
| IUPAC name | (2S,6R)-2,6-dimethyl-4-[2-methyl-3-[4-(2-methylbutan-2-yl)phenyl]propyl]morpholine |
| InChIKey | MQHLMHIZUIDKOO-AYHJJNSGSA-N |
| SMILES | CCC(C)(C)C1=CC=C(C=C1)CC(C)CN2C[C@H](O[C@H](C2)C)C |
Computed by PubChem (NCBI)