2-Methyl-6-(phenylethynyl)pyridine HCl
cas: 219911-35-0 — see every product listed under this CAS number, including other names
2-Methyl-6-(phenylethynyl)pyridine HCl (CAS 219911-35-0) is a chemical reagent available from Chemat. Available pack sizes: 50mg, 100mg, 250mg, 500mg. Offered by: Biosynth.
| brand | Biosynth |
|---|---|
| catalog number | FM64915-50mg |
| cas | 219911-35-0 |
| size | 50mg |
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Available pack sizes
| brand | size | price | |
|---|---|---|---|
| Biosynth | 50mg | price on request | |
| Biosynth | 100mg | price on request | |
| Biosynth | 250mg | price on request | |
| Biosynth | 500mg | price on request |
properties
| category | Research Chemicals |
|---|---|
| sub-category 1 | Building Blocks |
| sub-category 2 | Nitrogen Heterocycles |
| purity | No data |
| delivery time | 1-2 weeks |
2-methyl-6-(phenylethynyl)pyridine hydrochloride is a hydrochloride salt obtained by reaction of 2-methyl-6-(phenylethynyl)pyridine with one equivalent of hydrochloric acid. Potent and highly selective non-competitive antagonist at the mGlu5 receptor subtype (IC50 = 36 nM) and a positive allosteric modulator at mGlu4 receptors. Centrally active following systemic administration in vivo. Reverses mechanical hyperalgesia in the inflamed rat hind paw. It has a role as an anxiolytic drug and a metabotropic glutamate receptor antagonist. It contains a 2-methyl-6-(phenylethynyl)pyridinium(1+).
Source: ChEBI
| Molecular formula | C14H12ClN |
|---|---|
| Molecular weight | 229.70 g/mol |
| IUPAC name | 2-methyl-6-(2-phenylethynyl)pyridine;hydrochloride |
| InChIKey | PKDHDJBNEKXCBI-UHFFFAOYSA-N |
| SMILES | CC1=NC(=CC=C1)C#CC2=CC=CC=C2.Cl |
Computed by PubChem (NCBI)
Synonyms:
MPEP hydrochloride, 2-methyl-6-(phenylethynyl)pyridine hydrochloride, 6-Methyl-2-(phenylethynyl)pyridine hydrochloride, 2-methyl-6-(phenylethynyl)pyridinium chloride, 6-methyl-2-(phenylethynyl)pyridinium chloride, 6-Methyl-2-(phenylethynyl)pyridine, hydrochloride, Pyridine, 2-methyl-6-(phenylethynyl)-, hydrochloride, Pyridine, 6-methyl-2-(phenylethynyl)-, hydrochloride, MPEP HCl, MPEP (Hydrochloride)