6-Methyl-2-(phenylethynyl)pyridine hydro
cas: 219911-35-0 — see every product listed under this CAS number, including other names
6-Methyl-2-(phenylethynyl)pyridine hydro (CAS 219911-35-0) is a chemical reagent available from Chemat. Available pack sizes: 25MG, 5MG. Offered by: Sigma-Aldrich.
| brand | Sigma-Aldrich |
|---|---|
| catalog number | M5435-25MG |
| cas | 219911-35-0 |
| size | 25MG |
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Available pack sizes
| brand | size | price | |
|---|---|---|---|
| Sigma-Aldrich | 25MG | 1710.00 Pln | |
| Sigma-Aldrich | 5MG | 512.00 Pln |
2-methyl-6-(phenylethynyl)pyridine hydrochloride is a hydrochloride salt obtained by reaction of 2-methyl-6-(phenylethynyl)pyridine with one equivalent of hydrochloric acid. Potent and highly selective non-competitive antagonist at the mGlu5 receptor subtype (IC50 = 36 nM) and a positive allosteric modulator at mGlu4 receptors. Centrally active following systemic administration in vivo. Reverses mechanical hyperalgesia in the inflamed rat hind paw. It has a role as an anxiolytic drug and a metabotropic glutamate receptor antagonist. It contains a 2-methyl-6-(phenylethynyl)pyridinium(1+).
Source: ChEBI
| Molecular formula | C14H12ClN |
|---|---|
| Molecular weight | 229.70 g/mol |
| IUPAC name | 2-methyl-6-(2-phenylethynyl)pyridine;hydrochloride |
| InChIKey | PKDHDJBNEKXCBI-UHFFFAOYSA-N |
| SMILES | CC1=NC(=CC=C1)C#CC2=CC=CC=C2.Cl |
Computed by PubChem (NCBI)
Synonyms:
MPEP hydrochloride, 2-methyl-6-(phenylethynyl)pyridine hydrochloride, 6-Methyl-2-(phenylethynyl)pyridine hydrochloride, 2-methyl-6-(phenylethynyl)pyridinium chloride, 6-methyl-2-(phenylethynyl)pyridinium chloride, 6-Methyl-2-(phenylethynyl)pyridine, hydrochloride, Pyridine, 2-methyl-6-(phenylethynyl)-, hydrochloride, Pyridine, 6-methyl-2-(phenylethynyl)-, hydrochloride, MPEP HCl, MPEP (Hydrochloride)