cas: 219911-35-0 — see every product listed under this CAS number, including other names
2-Methyl-6-(phenylethynyl)pyridine hydrochloride, 98%, 98% (CAS 219911-35-0) is a chemical reagent available from Chemat. Available pack sizes: 1mg, 10mg, 25mg, 50mg, 100mg, 250mg. Offered by: Chemat.
| brand | Chemat |
|---|---|
| catalog number | Ch11BEB3-1mg |
| cas | 219911-35-0 |
| size | 1mg |
| availability | 0.6g |
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| brand | size | price | |
|---|---|---|---|
| Chemat | 1mg | 78.80 Pln | |
| Chemat | 10mg | 102.80 Pln | |
| Chemat | 25mg | 155.60 Pln | |
| Chemat | 50mg | 222.80 Pln | |
| Chemat | 100mg | 338.00 Pln | |
| Chemat | 250mg | 525.20 Pln |
| purity | 98% |
|---|---|
| delivery time | 3 weeks |
2-methyl-6-(phenylethynyl)pyridine hydrochloride is a hydrochloride salt obtained by reaction of 2-methyl-6-(phenylethynyl)pyridine with one equivalent of hydrochloric acid. Potent and highly selective non-competitive antagonist at the mGlu5 receptor subtype (IC50 = 36 nM) and a positive allosteric modulator at mGlu4 receptors. Centrally active following systemic administration in vivo. Reverses mechanical hyperalgesia in the inflamed rat hind paw. It has a role as an anxiolytic drug and a metabotropic glutamate receptor antagonist. It contains a 2-methyl-6-(phenylethynyl)pyridinium(1+).
Source: ChEBI
| Molecular formula | C14H12ClN |
|---|---|
| Molecular weight | 229.70 g/mol |
| IUPAC name | 2-methyl-6-(2-phenylethynyl)pyridine;hydrochloride |
| InChIKey | PKDHDJBNEKXCBI-UHFFFAOYSA-N |
| SMILES | CC1=NC(=CC=C1)C#CC2=CC=CC=C2.Cl |
Computed by PubChem (NCBI)