Products 2089314-64-5
CAS 2089314-64-5 appears in our catalog under these names: AOH1996, AOH1996/ 98.8% (existing batch purity), AOH1996 95%, N-(2-((2-(3-Methoxyphenoxy)phenyl)amino)-2-oxoethyl)-1-naphthamide, 98%, 98%. Offered by: GLPBio, TargetMol, Ambeed, Chemat. Available pack sizes: 5mg, 1mg, 10mg, 25mg, 50mg, 100mg, 500mg, 10g.
AOH1996 is a secondary carboxamide resulting from the formal condensation of the carboxy group of N-(naphthalen-1-ylcarbonyl)glycine with the amino group of 2-(3-methoxyphenoxy)aniline. It is a first-in-class small molecule inhibitor of PCNA, a protein essential for DNA replication and repair within tumours. It has a role as a PCNA inhibitor, an antineoplastic agent and an apoptosis inducer. It is a secondary carboxamide, a monomethoxybenzene, an aromatic ether, a diether and a naphthalenecarboxamide.
Source: ChEBI
| Molecular formula | C26H22N2O4 |
|---|---|
| Molecular weight | 426.5 g/mol |
| IUPAC name | N-[2-[2-(3-methoxyphenoxy)anilino]-2-oxoethyl]naphthalene-1-carboxamide |
| InChIKey | HDMONPHKMIZXDH-UHFFFAOYSA-N |
| SMILES | COC1=CC(=CC=C1)OC2=CC=CC=C2NC(=O)CNC(=O)C3=CC=CC4=CC=CC=C43 |
Computed by PubChem (NCBI)
Synonyms:
N-[2-[[2-(3-methoxyphenoxy)phenyl]amino]-2-oxoethyl]-1-Naphthalenecarboxamide, N-(2-((2-(3-Methoxyphenoxy)phenyl)amino)-2-oxoethyl)-1-naphthalenecarboxamide, N-(2-((2-(3-Methoxyphenoxy)phenyl)amino)-2-oxoethyl)-1-naphthamide, N-[2-[2-(3-methoxyphenoxy)anilino]-2-oxoethyl]naphthalene-1-carboxamide, 1-Naphthalenecarboxamide, N-[2-[[2-(3-methoxyphenoxy)phenyl]amino]-2-oxoethyl]-, N-[2-[[2-(3-Methoxyphenoxy)phenyl]amino]-2-oxoethyl]-1-naphthamide, N-{2-[2-(3-methoxyphenoxy)anilino]-2-oxoethyl}naphthalene-1-carboxamide, orb1819088, N-[2-[[2-(3-methoxyphenoxy)phenyl]amino]-2-oxoethyl]-, N-(2-(2-(3-Methoxyphenoxy)phenylamino)-2-oxoethyl)-1-naphthamide