Afatinib, Free Base, 99%
cas: 850140-72-6 — see every product listed under this CAS number, including other names
Afatinib, Free Base, 99% (CAS 850140-72-6) is a chemical reagent available from Chemat. Available pack sizes: 250mg. Offered by: Fluorochem.
| brand | Fluorochem |
|---|---|
| catalog number | F050665-250MG |
| cas | 850140-72-6 |
| size | 250mg |
| availability | In Stock UK |
Documents:
Safety Data Sheet (MSDS)
Need more information?
Ask us about this product — we're happy to help.
Available pack sizes
| brand | size | price | |
|---|---|---|---|
| Fluorochem | 250mg | 1362.04 Pln |
properties
| purity | 99% |
|---|---|
| dual use | No |
| currency | EUR |
| delivery time | 1-2 weeks |
| category | Odczynniki chemiczne |
Afatinib is a quinazoline compound having a 3-chloro-4-fluoroanilino group at the 4-position, a 4-dimethylamino-trans-but-2-enamido group at the 6-position, and an (S)-tetrahydrofuran-3-yloxy group at the 7-position. Used (as its dimaleate salt) for the first-line treatment of patients with metastatic non-small cell lung cancer. It has a role as an antineoplastic agent and a tyrosine kinase inhibitor. It is a secondary carboxamide, a member of furans, an aromatic ether, an organofluorine compound, a member of quinazolines, a tertiary amino compound, an enamide and a member of monochlorobenzenes.
Source: ChEBI
| Molecular formula | C24H25ClFN5O3 |
|---|---|
| Molecular weight | 485.9 g/mol |
| IUPAC name | (E)-N-[4-(3-chloro-4-fluoroanilino)-7-[(3S)-oxolan-3-yl]oxyquinazolin-6-yl]-4-(dimethylamino)but-2-enamide |
| InChIKey | ULXXDDBFHOBEHA-CWDCEQMOSA-N |
| SMILES | CN(C)C/C=C/C(=O)NC1=C(C=C2C(=C1)C(=NC=N2)NC3=CC(=C(C=C3)F)Cl)O[C@H]4CCOC4 |
Computed by PubChem (NCBI)