Products 3094-09-5
CAS 3094-09-5 appears in our catalog under these names: 5-Fluoro-5''-deoxyuridine, 5-Fluoro-5'-deoxyuridine, 5’-Deoxy-5-fluorouridine, >95% (HPLC), 5'-Deoxy-5-fluorouridine, 98%, 98%, 1-(5-Deoxy-beta-D-ribofuranosyl)-5-fluoropyrimidine-2,4(1H,3H)-dione (5'-Deoxy-5-fluorouridine). Offered by: Chemat, Thermo Scientific (Acros), Sigma-Aldrich, TRC, Mikromol. Available pack sizes: 100mg, 1g, 5g, 250MG, 25MG, 10mg, 50mg, 25g.
Doxifluridine is a pyrimidine 5'-deoxyribonucleoside that is 5-fluorouridine in which the hydroxy group at the 5' position is replaced by a hydrogen. It is an oral prodrug of the antineoplastic agent 5-fluorouracil. Designed to circumvent the rapid degradation of 5-fluorouracil by dihydropyrimidine dehydrogenase in the gut wall, it is converted into 5-fluorouracil in the presence of pyrimidine nucleoside phosphorylase. It has a role as an antimetabolite, an antineoplastic agent and a prodrug. It is an organofluorine compound and a pyrimidine 5'-deoxyribonucleoside.
Source: ChEBI
| Molecular formula | C9H11FN2O5 |
|---|---|
| Molecular weight | 246.19 g/mol |
| IUPAC name | 1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-methyloxolan-2-yl]-5-fluoropyrimidine-2,4-dione |
| InChIKey | ZWAOHEXOSAUJHY-ZIYNGMLESA-N |
| SMILES | C[C@@H]1[C@H]([C@H]([C@@H](O1)N2C=C(C(=O)NC2=O)F)O)O |
Computed by PubChem (NCBI)