Entecavir 98%

cas: 142217-69-4 — see every product listed under this CAS number, including other names

Entecavir 98% (CAS 142217-69-4) is a chemical reagent available from Chemat. Available pack sizes: 5mg, 10mg, 25mg, 50mg, 100mg, 250mg, 1g, 5g. Offered by: Ambeed.

brandAmbeed
catalog numberA948237-5mg
cas142217-69-4
size5mg
Documents: Safety Data Sheet (MSDS)

Available pack sizes

brand size price
Ambeed 5mg 175.69 Pln
Ambeed 10mg 203.50 Pln
Ambeed 25mg 231.31 Pln
Ambeed 50mg 270.25 Pln
Ambeed 100mg 309.19 Pln
Ambeed 250mg 364.81 Pln
Ambeed 1g 565.06 Pln
Ambeed 5g 1822.19 Pln

properties

purity98%
delivery time 1-2 weeks
ambeed catalog no.A948237
Structural formula: {0} (CAS {1})

Entecavir (anhydrous) is guanine substituted at the 9 position by a 4-hydroxy-3-(hydroxymethyl)-2-methylidenecyclopentyl group. A synthetic analogue of 2'-deoxyguanosine, it is a nucleoside reverse transcriptase inhibitor with selective antiviral activity against hepatitis B virus. Entecavir is phosphorylated intracellularly to the active triphosphate form, which competes with deoxyguanosine triphosphate, the natural substrate of hepatitis B virus reverse transcriptase, inhibiting every stage of the enzyme's activity, although it has no activity against HIV. It is used for the treatment of chronic hepatitis B. It has a role as an antiviral drug and an EC 2.7.7.49 (RNA-directed DNA polymerase) inhibitor. It is a primary alcohol, a member of 2-aminopurines, an oxopurine and a secondary alcohol.

Source: ChEBI

Identity
Molecular formulaC12H15N5O3
Molecular weight277.28 g/mol
IUPAC name2-amino-9-[(1S,3R,4S)-4-hydroxy-3-(hydroxymethyl)-2-methylidenecyclopentyl]-1H-purin-6-one
InChIKeyQDGZDCVAUDNJFG-FXQIFTODSA-N
SMILESC=C1[C@H](C[C@@H]([C@H]1CO)O)N2C=NC3=C2N=C(NC3=O)N

Computed by PubChem (NCBI)

Synonyms: Entecavir, Baraclude, anhydrous entecavir, Entecavir anhydrous, entecavir (anhydrous), Entecavirum, Entecavir [USAN:INN], Entecavir (INN), Entecavir [INN], Entecavir sodium
Related forms of this compound
2-amino-9-[(1R,3R,4R)-4-hydroxy-3-(hydroxymethyl)-2-methylidenecyclopentyl]-1H-purin-6-one C12H15N5O3
2-amino-9-[(1S,3S,4R)-4-hydroxy-3-(hydroxymethyl)-2-methylidenecyclopentyl]-1H-purin-6-one C12H15N5O3
2-amino-9-[(1S,3S,4S)-4-hydroxy-3-(hydroxymethyl)-2-methylidenecyclopentyl]-1H-purin-6-one C12H15N5O3
2-amino-9-[(1S,3S,4S)-4-hydroxy-3-(hydroxymethyl)-2-methylidenecyclopentyl]-1H-purin-6-one C12H15N5O3
2-amino-9-[(1R,3S,4R)-4-hydroxy-3-(hydroxymethyl)-2-methylidenecyclopentyl]-1H-purin-6-one C12H15N5O3
2-amino-9-[(1R,3R,4S)-4-hydroxy-3-(hydroxymethyl)-2-methylidenecyclopentyl]-1H-purin-6-one C12H15N5O3
Isomers (same molecular formula)
2-amino-5-[[[(1S,4S,5R)-4,5-dihydroxycyclopent-2-en-1-yl]amino]methyl]-3,7-dihydropyrrolo[2,3-d]pyrimidin-4-one C12H15N5O3
N'-hydroxy-6-[3-(3-methyl-1,2-oxazol-5-yl)propoxy]pyridazine-3-carboximidamide C12H15N5O3

Also listed as

Entecavir, 98% Combi-blocks CAS 142217-69-4
Entecavir Chemat Brand CAS 142217-69-4
Entecavir, >95% (HPLC) TRC CAS 142217-69-4
Entecavir/ 99.72% (existing batch purity) TargetMol CAS 142217-69-4
Entecavir–d2 GLPBio CAS 142217-69-4
Entecavir (BMS200475) GLPBio CAS 142217-69-4
2-Amino-1,9-dihydro-9-[(1S,3R,4S)-4-hydroxy-3-(hydroxymethyl)-2-methylenecyclopentyl]-6H-purin-6-one, 95+%, 95+% Chemat CAS 142217-69-4
Entecavir, 99.98% MedChemExpress CAS 142217-69-4
Entecavir, 95% Fluorochem CAS 142217-69-4