FG–4592 (ASP1517)
cas: 808118-40-3 — see every product listed under this CAS number, including other names
FG–4592 (ASP1517) (CAS 808118-40-3) is a chemical reagent available from Chemat. Available pack sizes: 10mg, 100mg, 200mg, 10mM (in 1ml dmso), 50mg, 500mg. Offered by: GLPBio.
| brand | GLPBio |
|---|---|
| catalog number | GC13139-10 |
| cas | 808118-40-3 |
| size | 10mg |
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Available pack sizes
| brand | size | price | |
|---|---|---|---|
| GLPBio | 10mg | 587.68 Pln | |
| GLPBio | 100mg | 1041.69 Pln | |
| GLPBio | 200mg | 1378.68 Pln | |
| GLPBio | 10mM (in 1ml dmso) | 583.00 Pln | |
| GLPBio | 50mg | 905.95 Pln | |
| GLPBio | 500mg | 1860.77 Pln |
properties
| purity | No data |
|---|---|
| delivery time | To be confirmed by Chemat |
Roxadustat is an N-acylglycine resulting from the formal condensation of the amino group of glycine with the carboxy group of 4-hydroxy-1-methyl-7-phenoxyisoquinoline-3-carboxylic acid. It is an inhibitor of hypoxia inducible factor prolyl hydroxylase (HIF-PH). It has a role as an EC 1.14.11.29 (hypoxia-inducible factor-proline dioxygenase) inhibitor and an EC 1.14.11.2 (procollagen-proline dioxygenase) inhibitor. It is a N-acylglycine, a member of isoquinolines and an aromatic ether.
Source: ChEBI
| Molecular formula | C19H16N2O5 |
|---|---|
| Molecular weight | 352.3 g/mol |
| IUPAC name | 2-[(4-hydroxy-1-methyl-7-phenoxyisoquinoline-3-carbonyl)amino]acetic acid |
| InChIKey | YOZBGTLTNGAVFU-UHFFFAOYSA-N |
| SMILES | CC1=C2C=C(C=CC2=C(C(=N1)C(=O)NCC(=O)O)O)OC3=CC=CC=C3 |
Computed by PubChem (NCBI)
Synonyms:
Roxadustat, Evrenzo, roxadustatum, (((4-Hydroxy-1-methyl-7-phenoxyisoquinolin-3-yl)carbonyl)amino)acetic acid, N-[(4-hydroxy-1-methyl-7-phenoxyisoquinolin-3-yl)carbonyl]glycine, 2-((4-hydroxy-1-methyl-7-(phenoxy)isoquinoline-3-carbonyl)amino)acetic acid, 2-[[4-hydroxy-1-methyl-7-(phenoxy)isoquinoline-3-carbonyl]amino]acetic acid, N-[(4-Hydroxy-1-methyl-7-phenoxy-3-isoquinolinyl)carbonyl]glycine, Roxadustat (FG-4592), 2-[(4-hydroxy-1-methyl-7-phenoxyisoquinoline-3-carbonyl)amino]acetic acid