Roxadustat (Standard)
cas: 808118-40-3 — see every product listed under this CAS number, including other names
Roxadustat (Standard) (CAS 808118-40-3) is a chemical reagent available from Chemat. Available pack sizes: 25 mg, 50 mg, 100 mg, 5 mg, 10 mg. Offered by: MedChemExpress.
| brand | MedChemExpress |
|---|---|
| catalog number | HY-13426R-25 mg |
| cas | 808118-40-3 |
| size | 25 mg |
| availability | Get quote |
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Available pack sizes
| brand | size | price | |
|---|---|---|---|
| MedChemExpress | 25 mg | 1341.37 Pln | |
| MedChemExpress | 50 mg | 1833.64 Pln | |
| MedChemExpress | 100 mg | 2344.48 Pln | |
| MedChemExpress | 5 mg | 575.11 Pln | |
| MedChemExpress | 10 mg | 802.67 Pln |
properties
| delivery time | over 3 weeks |
|---|---|
| purity | no data |
Roxadustat is an N-acylglycine resulting from the formal condensation of the amino group of glycine with the carboxy group of 4-hydroxy-1-methyl-7-phenoxyisoquinoline-3-carboxylic acid. It is an inhibitor of hypoxia inducible factor prolyl hydroxylase (HIF-PH). It has a role as an EC 1.14.11.29 (hypoxia-inducible factor-proline dioxygenase) inhibitor and an EC 1.14.11.2 (procollagen-proline dioxygenase) inhibitor. It is a N-acylglycine, a member of isoquinolines and an aromatic ether.
Source: ChEBI
| Molecular formula | C19H16N2O5 |
|---|---|
| Molecular weight | 352.3 g/mol |
| IUPAC name | 2-[(4-hydroxy-1-methyl-7-phenoxyisoquinoline-3-carbonyl)amino]acetic acid |
| InChIKey | YOZBGTLTNGAVFU-UHFFFAOYSA-N |
| SMILES | CC1=C2C=C(C=CC2=C(C(=N1)C(=O)NCC(=O)O)O)OC3=CC=CC=C3 |
Computed by PubChem (NCBI)
Synonyms:
Roxadustat, Evrenzo, roxadustatum, (((4-Hydroxy-1-methyl-7-phenoxyisoquinolin-3-yl)carbonyl)amino)acetic acid, N-[(4-hydroxy-1-methyl-7-phenoxyisoquinolin-3-yl)carbonyl]glycine, 2-((4-hydroxy-1-methyl-7-(phenoxy)isoquinoline-3-carbonyl)amino)acetic acid, 2-[[4-hydroxy-1-methyl-7-(phenoxy)isoquinoline-3-carbonyl]amino]acetic acid, N-[(4-Hydroxy-1-methyl-7-phenoxy-3-isoquinolinyl)carbonyl]glycine, Roxadustat (FG-4592), 2-[(4-hydroxy-1-methyl-7-phenoxyisoquinoline-3-carbonyl)amino]acetic acid